Copper peptide
A naturally occurring copper-binding tripeptide studied in skin and extracellular-matrix research.
A naturally occurring copper-binding tripeptide studied in skin and extracellular-matrix research.
Evidence map
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu.
A Torilis japonica Extract-GHK-Cu Complex Attenuates Th2 Cytokines and Promotes Keratinocyte Recovery: A Potential Antioxidant Strategy for Atopic Dermatitis.
Copper peptide activated cascade catalysis for glucose regulation and hypoxia reversing in infected diabetic wound healing.
Middle-aged mice treated with GHK-Cu peptide administered intraperitoneally or intranasally show behavioral rescue but divergent hippocampal aging programs.
Microenvironment-responsive injectable dynamic hydrogel for sequential antioxidant and tissue regeneration therapy of radiation-induced skin injury.
The Laccase-like Property of GHK-Cu and Its Applications in Colorimetric Sensing of Phenolic Compounds.
Phenothiazine-Based Cu(II)-Selective Fluorescent Sensor: GHK-Cu Sensing Applications
Intermediate Cu(II)-Thiolate Species in the Reduction of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II) Reduction
In Vitro and in Vivo Studies of pH-Sensitive GHK-Cu-Incorporated Polyaspartic and Polyacrylic Acid Superabsorbent Polymer
Antioxidant and anti-inflammation effect of GHK-Cu in bleomycin-induced pulmonary fibrosis
Efficient Ternary Polymer Solar Cells with Tunable Crystallinity and Phase Separation of Active Layers via Incorporating GHK-Cu
X-RAY STUDY OF Cu(II)GHK COPPER-CONTAINING PEPTIDE COMPLEXES
GHK-Cu NA MEDICINA REGENERATIVA: MECANISMOS MOLECULARES, APLICAÇÕES CLÍNICAS E PERSPECTIVAS TERAPÊUTICAS EM UMA METANÁLISE
The role of copper tripeptide (GHK-Cu) in the process of skin regeneration
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health
Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Self‐Assembled Fluorescent and Antibacterial GHK‐Cu Nanoparticles for Wound Healing Applications
GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis
Liposomes as Carriers of GHK-Cu Tripeptide for Cosmetic Application
GHK-Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes
Peptides in Regenerative Medicine: A Comprehensive Review of Clinical Applications in Tissue Repair and Chronic Pain Management.
Peptide Supplements and Their Therapeutic Applications in Sports Medicine.
The Regenerative Potential of GHK-Cu in Aesthetic Medicine.
A tea exosome-integrated self‑oxygenating cascade chitosan/oxidized alginate hydrogel for remodeling the hyperglycemic and hypoxic microenvironment in diabetic wound healing.
Augmented Skin Beneficial Effects of Thermus Thermophilus and Bacillus Subtilis Mixed-Culture Ferment Extract by Tripeptide GHK-Cu.
A Torilis japonica Extract-GHK-Cu Complex Attenuates Th2 Cytokines and Promotes Keratinocyte Recovery: A Potential Antioxidant Strategy for Atopic Dermatitis.
Copper peptide activated cascade catalysis for glucose regulation and hypoxia reversing in infected diabetic wound healing.
Hierarchical regulation and mechanism of "open-hollow-fibrous network" structures: Osteogenic-angiogenic coupling responses of poly(γ-benzyl-L-glutamate) microspheres.
Two-Part Study of the Effects of the X39 Patch on Circulating GHK and GHK-Cu Levels in Healthy Adults
Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types.
Topical GHK-Cu Gel for Acute Skin Wound Healing
GHK-Cu as a Bioactive Metallopeptide and Drug-Delivery Cargo: Coordination Chemistry, Formulation Science, Therapeutic Evidence, and a Translational Roadmap.
A Systematic Review of the Mechanisms and Therapeutic Applications of GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper Complex) in Topical Microneedle Delivery: A Case for Expanded Clinical Trials.
A Systematic Review of the Mechanisms and Therapeutic Applications of GHK-Cu (Glycyl-L-Histidyl-L-Lysine-Copper Complex) in Topical Microneedle Delivery: A Case for Expanded Clinical Trials.
GHK-Cu as a Bioactive Metallopeptide and Drug-Delivery Cargo: Coordination Chemistry, Formulation Science, Therapeutic Evidence, and a Translational Roadmap.
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This study will evaluate whether a topical gel containing GHK-Cu (a copper(II)-peptide complex) can safely speed up healing of small, standardized skin wounds in healthy adults compared with a matching vehicle gel. Participants will receive two small punch-biopsy...
The goal of this clinical trial is to investigate GHK and GHK-Cu blood levels pre- and post-intervention in healthy adults, and to investigate the efficacy of X39 patch on GHK and GHK-Cu blood levels in healthy adults compared...
This is a phase IV, unblinded, open-label study assessing the impact on skin quality, hydration, and barrier of three (3) Hydrafacial treatments in healthy adults of Fitzpatrick Skin Types I \& II, III, IV, V \& VI, 30...
Su J, Zhang Y, Cao Y, Ren T, Zhang K, Chen D, Yin J
Wang J, Tao K, Huang H, Chang H
Huang ZJ, Huang RF, Jiao PP, Zheng S, Wang M, Teng FW, Chen T, Zhou ZS, Wang GH, Jiao GL
Najafi N, Maatouk H, Vardanyan KG, Vartanian KB, Agrawal DK
Mateescu DM, Gavrilescu DM, Mincioaga RI, Pah AM, Toma AO, Serban DV, Avram CA, Craciun ML, Enache B, Muresan CO
Luansritisakul C, Chiang MC, Burns SL, Fonseca ACG
Mokhtar J, Mohamad B, Haddad J, Said A, Menon A, Kreutz-Rodrigues L, Vyas KS, Cetrulo CL Jr, Lellouch AG
Xie LH, Zhou XH, Wen WQ, Wang W, Gui P, Li L, Wang GH
Tewari K, Liu TP, Im C, Hamad C, Petrigliano F, Cheung EC, Kremen TJ Jr
Jeon S, Maeng J, Lee J, Kim YM, Nam G
Mateescu DM, Gavrilescu DM, Mincioaga RI, Pah AM, Toma AO, Serban DV, Avram CA, Craciun ML, Enache B, Muresan CO · Pharmaceutics
Yu X, Yang T, Bei Z, Liu J, Song Y, Wang Q, Li J, Liang S, Qian Z · Bioactive materials
Wang J, Tao K, Huang H, Chang H · Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for...
Huang ZJ, Huang RF, Jiao PP, Zheng S, Wang M, Teng FW, Chen T, Zhou ZS, Wang GH, Jiao GL · Materials today. Bio
Najafi N, Maatouk H, Vardanyan KG, Vartanian KB, Agrawal DK · Archives of internal medicine research
Jeon S, Maeng J, Lee J, Kim YM, Nam G · Antioxidants (Basel, Switzerland)
Mazzola J, Rosenfeld M, Tucker M, Wezeman J, Ladiges W, Liao G · Research square
Chen JS, Zhu H, Chai TQ, Yang FQ · Biosensors
Objetivo: Sistematizar as evidências científicas sobre o tripeptídeo complexo de cobre GHK-Cu (glicil-L-histidil-L-lisina-Cu2+) na medicina regenerativa, analisando seus mecanismos moleculares, aplicações clínicas atuais e perspectivas terapêuticas futuras. Métodos: Realizou-se uma revisão sistemática com meta-análise seguindo as diretrizes PRISMA...
A.S. Polonskaia Polonskaia, E.A. Shatokhina Shatokhina, L.S. Kruglova Kruglova · Bionika Media
Gang Hou, Xiaoming Zhou · European Respiratory Society
· NIIC SB RAS
· American Chemical Society (ACS)
· American Chemical Society (ACS)
· American Chemical Society (ACS)
· American Chemical Society (ACS)
Michał Dymek, Karolina Olechowska, Katarzyna Hąc-Wydro, Elżbieta S. Sikora · Pharmaceutics · 31 citations
Wenhui Ma, Meng Li, Haifeng Ma, Wei Li, Li Liu, Yan Yin et al. · Life Sciences · 87 citations
Leming Sun, Aipeng Li, Yanzi Hu, Yang Li, Li Shang, Lianbing Zhang · Particle & Particle Systems Characterization · 47 citations
Loren Pickart, Anna Margolina · International Journal of Molecular Sciences · 153 citations
Xinying Wang, Baoquan Liu, Qiang Xu, Haiyang Sun, Meijun Shi, Dan Wang et al. · Wound Repair and Regeneration · 52 citations
Jeong-Ran Park, Hanbyeol Lee, Seok-In Kim, Se‐Ran Yang · Oncotarget · 60 citations
Loren Pickart, Jessica Michelle Vasquez-Soltero, Anna Margolina · Cosmetics · 49 citations
Loren Pickart, Jessica Michelle Vasquez-Soltero, Anna Margolina · Oxidative Medicine and Cellular Longevity · 108 citations
Live discovery
Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
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