Research context
A synthetic ghrelin-receptor agonist used in laboratory endocrine research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Growth-hormone research
GHRP-2
A synthetic ghrelin-receptor agonist used in laboratory endocrine research.
32 connected records32 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
pubmed 2026
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M · Frontiers in endocrinology
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
pmc 2026
E. N. Semenistaya, Irina Zvereva, Andreas Thomas, Mario Thevis, Grigory I. Krotov, Grigory M. Rodchenkov · Drug Testing and Analysis · 49 citations
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
openalex 2015
Okada N, Nakagawa T, Murahashi N, Kurosu T, Kusuda S, Kaneko C, Hishida Y, Nakamura Y, Asai S, Yokota K, Sone M
Differentiating hypothalamic from pituitary adrenal insufficiency: underlying causes and diagnostic utility of the corticotropin-releasing hormone and growth hormone-releasing peptide-2 stimulation tests.
pubmed
Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K, Masuda Y, Omura D, Sakurada Y, Matsuda Y, Hasegawa T, Honda H, Tokumasu K, Ueda K, Otsuka F
Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.
pubmed
Sato T
One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.
pubmed 2025
Kondo T, Suga H, Takeuchi K, Fuse Y, Sato Y, Hirose T, Hideyuki H, Nagata Y, Saito R
Benchmark for Setting ACTH Cell Dosage in Clinical Regenerative Medicine for Post-Operative Hypopituitarism.
pubmed
Li Y, Yao L, Zhang C, Li T, Wang D, Li J, Huang Y, Tang X
Growth Hormone-Releasing Peptide 2 May Be Associated With Decreased M1 Macrophage Production and Increased Histologic and Biomechanical Tendon-Bone Healing Properties in a Rat Rotator Cuff Tear Model.
pubmed 2025
Teramoto S, Tahara S, Hattori Y, Kondo A, Morita A
Assessment of anterior pituitary reserve capacity based on growth hormone response to growth hormone-releasing peptide-2 test in the elderly.
pubmed 2023
Celichowska M, Miedziaszczyk M, Lacka K
Pharmacotherapy in Cachexia: A Review of Endocrine Abnormalities and Steroid Pharmacotherapy.
pubmed 2022
Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K, Masuda Y, Omura D, Sakurada Y, Matsuda Y, Hasegawa T, Honda H, Tokumasu K, Ueda K, Otsuka F · International journal of molecular sciences
Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.
pmc
Iwata N, Kato Y, Murase O, Tsumura T, Fujisawa H, Sugimura Y · Journal of the Endocrine Society
MON-030 A Case of Idiopathic Arginine Vasopressin Deficiency Diagnosed Following Worsening of Thirst, Polydipsia, and Polyuria During Chemotherapy.
pmc
Sato T · Cureus
One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.
pmc 2025
Kondo T, Suga H, Takeuchi K, Fuse Y, Sato Y, Hirose T, Hideyuki H, Nagata Y, Saito R · Diseases (Basel, Switzerland)
Benchmark for Setting ACTH Cell Dosage in Clinical Regenerative Medicine for Post-Operative Hypopituitarism.
pmc
Seki Y, Morimoto S, Bokuda K, Watanabe D, Watanabe S, Yamashita K, Takano N, Ichihara A · Journal of the Endocrine Society
THU069 Growth Hormone Secretion And Serum High-sensitivity C-reactive Protein Levels In Adult Patients With Non-functioning Pituitary Tumors.
pmc
Seki Y, Takano N, Yamashita K, Bokuda K, Sasaki N, Ishikawa T, Kimura M, Watanabe S, Watanabe D, Morimoto S, Ichihara A · Journal of the Endocrine Society
ODP323 Increased Serum High-Sensitivity C-Reactive Protein Levels in Adult Growth Hormone Deficient Patients with Non-Functioning Pituitary Tumors.
pmc
Seki Y, Ichihara A · PloS one
Association between overweight and growth hormone secretion in patients with non-functioning pituitary tumors.
pmc 2026
W. C. Huhn · The Endocrine Society
Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus
crossref 1993
Cyril Y. Bowers · Springer US
GHRP-GH Secretagogues
crossref 1999
Growth hormone releasing peptides (GHRPs) stimulate secretion of endogenous growth hormone and are listed on the World Anti‐Doping Agency (WADA) Prohibited List. To develop an effective method for GHRPs anti‐doping control we have investigated metabolites of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin in urine after...
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
crossref 2015
Holly D. Cox, Cole M. Hughes, Daniel Eichner · Wiley
Detection of GHRP‐2 and GHRP‐6 in urine samples from athletes
crossref 2015
C. Y. Bowers · Humana Press
GHRP Historical Perspective: Basic and Clinical
crossref
Fibrosis is defined as the pathological accumulation of extracellular matrix proteins (ECMs) during the tissue repair response to an injury, which interferes with the functioning of the damaged organ or tissue, which is the underlying cause of multiple disorders that lead to high morbidity and...
Avances en Biotecnología: péptido liberador de hormonas de crecimiento 6 (GHRP-6)
crossref 2021
Svetozar Damjanović, Vera Popović, Milan Petakov, Marina Djurović, Carlos Dieguez, Felipe F. Casanueva · Walter de Gruyter GmbH
Pituitary Enlargement Due to Primary Hypothyroidism: Growth Hormone Response to GHRH, GHRP-6 and GHRH Plus GHRP-6
crossref 1996
Chen Chen, Iain J. Clarke · Elsevier
Intracellular GHRP Signalling
crossref 1999
Miriam Granado, Teresa Priego, Ana Isabel Martı́n, M.A. Villanúa, Asunción López‐Calderón · American Journal of Physiology-Endocrinology and Metabolism · 173 citations
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats
openalex 2004
Greet Van den Berghe, Robert C. Baxter, Frank Weekers, Pieter Jozef Wouters, Cyril Y. Bowers, Ali Iranmanesh et al. · Clinical Endocrinology · 136 citations
The combined administration of GH‐releasing peptide‐2 (GHRP‐2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP‐2 alone
openalex 2002
Andreas Thomas, Maxie Kohler, Joachim Mester, Hans Geyer, Wilhelm Schänzer, Michael Petrou et al. · Drug Testing and Analysis · 62 citations
Identification of the growth‐hormone‐releasing peptide‐2 (GHRP‐2) in a nutritional supplement
openalex 2010
Emanuela Arvat, Lidia Di Vito, Barbara Maccagno, Fabio Broglio, Muni Franklin Boghen, Romano Deghenghi et al. · Peptides · 88 citations
Effects of GHRP-2 and Hexarelin, Two Synthetic GH-Releasing Peptides, on GH, Prolactin, ACTH and Cortisol Levels in Man. Comparison with the Effects of GHRH, TRH and hCRH
openalex 1997
CYRIL Y. BOWERS, Ramona Granda-Ayala · PubMed · 24 citations
GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.
openalex 1996
Blandine Laferrère, Cynthia Abraham, Colleen D. Russell, Cyril Y. Bowers · The Journal of Clinical Endocrinology & Metabolism · 55 citations
Growth Hormone Releasing Peptide-2 (GHRP-2), Like Ghrelin, Increases Food Intake in Healthy Men
openalex 2005
Danxing Wu, Chen Chen, J Zhang, C. Y. Bowers, Iain James Clarke · Journal of Endocrinology · 56 citations
The effects of GH-releasing peptide-6 (GHRP-6) and GHRP-2 on intracellular adenosine 3′,5′-monophosphate (cAMP) levels and GH secretion in ovine and rat somatotrophs
openalex 1996
Connected data hub
Records with source provenance.
Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.
Open Access Article
8 recordspmcAutomated import
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M · Frontiers in endocrinology
pmcAutomated import
Association between overweight and growth hormone secretion in patients with non-functioning pituitary tumors.
Seki Y, Ichihara A · PloS one
pmcAutomated import
One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.
Sato T · Cureus
pmcAutomated import
Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.
Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K, Masuda Y, Omura D, Sakurada Y, Matsuda Y, Hasegawa T, Honda H, Tokumasu K, Ueda K, Otsuka F · International journal of molecular sciences
pmcAutomated import
MON-030 A Case of Idiopathic Arginine Vasopressin Deficiency Diagnosed Following Worsening of Thirst, Polydipsia, and Polyuria During Chemotherapy.
Iwata N, Kato Y, Murase O, Tsumura T, Fujisawa H, Sugimura Y · Journal of the Endocrine Society
pmcAutomated import
Benchmark for Setting ACTH Cell Dosage in Clinical Regenerative Medicine for Post-Operative Hypopituitarism.
Kondo T, Suga H, Takeuchi K, Fuse Y, Sato Y, Hirose T, Hideyuki H, Nagata Y, Saito R · Diseases (Basel, Switzerland)
pmcAutomated import
THU069 Growth Hormone Secretion And Serum High-sensitivity C-reactive Protein Levels In Adult Patients With Non-functioning Pituitary Tumors.
Seki Y, Morimoto S, Bokuda K, Watanabe D, Watanabe S, Yamashita K, Takano N, Ichihara A · Journal of the Endocrine Society
pmcAutomated import
ODP323 Increased Serum High-Sensitivity C-Reactive Protein Levels in Adult Growth Hormone Deficient Patients with Non-Functioning Pituitary Tumors.
Seki Y, Takano N, Yamashita K, Bokuda K, Sasaki N, Ishikawa T, Kimura M, Watanabe S, Watanabe D, Morimoto S, Ichihara A · Journal of the Endocrine Society
Publication
8 recordspubmedAutomated import
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M
pubmedAutomated import
Growth Hormone-Releasing Peptide 2 May Be Associated With Decreased M1 Macrophage Production and Increased Histologic and Biomechanical Tendon-Bone Healing Properties in a Rat Rotator Cuff Tear Model.
Li Y, Yao L, Zhang C, Li T, Wang D, Li J, Huang Y, Tang X
pubmedAutomated import
One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.
Sato T
pubmedAutomated import
Assessment of anterior pituitary reserve capacity based on growth hormone response to growth hormone-releasing peptide-2 test in the elderly.
Teramoto S, Tahara S, Hattori Y, Kondo A, Morita A
pubmedAutomated import
Pharmacotherapy in Cachexia: A Review of Endocrine Abnormalities and Steroid Pharmacotherapy.
Celichowska M, Miedziaszczyk M, Lacka K
pubmedAutomated import
Differentiating hypothalamic from pituitary adrenal insufficiency: underlying causes and diagnostic utility of the corticotropin-releasing hormone and growth hormone-releasing peptide-2 stimulation tests.
Okada N, Nakagawa T, Murahashi N, Kurosu T, Kusuda S, Kaneko C, Hishida Y, Nakamura Y, Asai S, Yokota K, Sone M
pubmedAutomated import
Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.
Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K, Masuda Y, Omura D, Sakurada Y, Matsuda Y, Hasegawa T, Honda H, Tokumasu K, Ueda K, Otsuka F
pubmedAutomated import
Benchmark for Setting ACTH Cell Dosage in Clinical Regenerative Medicine for Post-Operative Hypopituitarism.
Kondo T, Suga H, Takeuchi K, Fuse Y, Sato Y, Hirose T, Hideyuki H, Nagata Y, Saito R
Scholarly Work
8 recordscrossrefAutomated import
Avances en Biotecnología: péptido liberador de hormonas de crecimiento 6 (GHRP-6)
Fibrosis is defined as the pathological accumulation of extracellular matrix proteins (ECMs) during the tissue repair response to an injury, which interferes with the functioning of the damaged organ or tissue, which is the underlying cause of multiple...
crossrefAutomated import
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
Growth hormone releasing peptides (GHRPs) stimulate secretion of endogenous growth hormone and are listed on the World Anti‐Doping Agency (WADA) Prohibited List. To develop an effective method for GHRPs anti‐doping control we have investigated metabolites of GHRP‐1, GHRP‐2,...
crossrefAutomated import
Detection of GHRP‐2 and GHRP‐6 in urine samples from athletes
Holly D. Cox, Cole M. Hughes, Daniel Eichner · Wiley
crossrefAutomated import
GHRP-GH Secretagogues
Cyril Y. Bowers · Springer US
crossrefAutomated import
Intracellular GHRP Signalling
Chen Chen, Iain J. Clarke · Elsevier
crossrefAutomated import
Pituitary Enlargement Due to Primary Hypothyroidism: Growth Hormone Response to GHRH, GHRP-6 and GHRH Plus GHRP-6
Svetozar Damjanović, Vera Popović, Milan Petakov, Marina Djurović, Carlos Dieguez, Felipe F. Casanueva · Walter de Gruyter GmbH
crossrefAutomated import
Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus
W. C. Huhn · The Endocrine Society
crossrefAutomated import
GHRP Historical Perspective: Basic and Clinical
C. Y. Bowers · Humana Press
Article
8 recordsopenalexAutomated import
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
E. N. Semenistaya, Irina Zvereva, Andreas Thomas, Mario Thevis, Grigory I. Krotov, Grigory M. Rodchenkov · Drug Testing and Analysis · 49 citations
openalexAutomated import
Identification of the growth‐hormone‐releasing peptide‐2 (GHRP‐2) in a nutritional supplement
Andreas Thomas, Maxie Kohler, Joachim Mester, Hans Geyer, Wilhelm Schänzer, Michael Petrou et al. · Drug Testing and Analysis · 62 citations
openalexAutomated import
Growth Hormone Releasing Peptide-2 (GHRP-2), Like Ghrelin, Increases Food Intake in Healthy Men
Blandine Laferrère, Cynthia Abraham, Colleen D. Russell, Cyril Y. Bowers · The Journal of Clinical Endocrinology & Metabolism · 55 citations
openalexAutomated import
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats
Miriam Granado, Teresa Priego, Ana Isabel Martı́n, M.A. Villanúa, Asunción López‐Calderón · American Journal of Physiology-Endocrinology and Metabolism · 173 citations
openalexAutomated import
The combined administration of GH‐releasing peptide‐2 (GHRP‐2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP‐2 alone
Greet Van den Berghe, Robert C. Baxter, Frank Weekers, Pieter Jozef Wouters, Cyril Y. Bowers, Ali Iranmanesh et al. · Clinical Endocrinology · 136 citations
openalexAutomated import
Effects of GHRP-2 and Hexarelin, Two Synthetic GH-Releasing Peptides, on GH, Prolactin, ACTH and Cortisol Levels in Man. Comparison with the Effects of GHRH, TRH and hCRH
Emanuela Arvat, Lidia Di Vito, Barbara Maccagno, Fabio Broglio, Muni Franklin Boghen, Romano Deghenghi et al. · Peptides · 88 citations
openalexAutomated import
GHRP-2, GHRH and SRIF interrelationships during chronic administration of GHRP-2 to humans.
CYRIL Y. BOWERS, Ramona Granda-Ayala · PubMed · 24 citations
openalexAutomated import
The effects of GH-releasing peptide-6 (GHRP-6) and GHRP-2 on intracellular adenosine 3′,5′-monophosphate (cAMP) levels and GH secretion in ovine and rat somatotrophs
Danxing Wu, Chen Chen, J Zhang, C. Y. Bowers, Iain James Clarke · Journal of Endocrinology · 56 citations
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Recent PubMed records
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.PMID 42862021 · 2026 Sep 30Differentiating hypothalamic from pituitary adrenal insufficiency: underlying causes and diagnostic utility of the corticotropin-releasing hormone and growth hormone-releasing peptide-2 stimulation tests.PMID 42732957 · 2026 Sep 11The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.PMID 42395176 · 2026Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone.PMID 41596479 · 2026 Jan 14One Case of Sudden Isolated Adrenocorticotropic Hormone (ACTH) Deficiency Diagnosed Based on Repeated Hypoglycemic Attacks.PMID 40677481 · 2025 JunRegistered clinical studies
Reviewed UniProt records
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