Mitochondrial research
A mitochondria-derived peptide studied in cellular stress and healthy-ageing research.
A mitochondria-derived peptide studied in cellular stress and healthy-ageing research.
Evidence map
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
[Effects of cardiac rehabilitation and predictive value of Humanin/CRP ratio in patients with acute exacerbation of chronic heart failure].
Mitokines as bioenergetic stress signals in cardiovascular disease: mitochondrial communication, endocrine adaptation, and translational implications.
Low Dose Ketamine Preconditions Astrocyte Mitochondria to Achieve Antidepressant Efficacy via Adenosine, Humanin, and Melatonin Upregulation and Efflux.
S14G-humanin attenuates renal ischaemia-reperfusion injury, potentially through activation of STAT3 and ERK1/2 signalling pathways in rats.
A self-assembled peptide forms α-helical nanopores for ultrasensitive biomarker profiling.
AGEs-RAGE Axis and Mitochondrial-Derived Peptides in Advanced Chronic Kidney Disease: Interconnected Pathways Beyond Inflammation and Nutrition.
Mitochondrial-derived peptides (MDPs) activated by physical exercise as therapeutic targets for metabolic disorders: A systematic review.
Dihydroquercetin alleviates mitochondrial dysfunction and inhibits NLRP3-mediated pyroptosis in primary hepatocytes from chronic liver failure patients.
Clinical Value of Plasma Humanin in Acute Kidney Injury
Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment
Humanin's Value for Early Diagnosis and Short-term Prognosis in Patients With AKI After Heart Transplantation
Comparison of the Effects of General Anesthesia and Combined Spinal-Epidural Anesthesia on Ferroptosis, Humanin and MOTS-c Levels in Renal Transplantation
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Humanin Isoforms in Cardiac Muscle and Blood Plasma and Major Complications After Cardiac Operation
IVF Outcome in Polycystic Ovary Syndrome Patients
Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent Klebsiella pneumoniae Infection.
Mitochondrial Peptide SHLP2 Limits Poly(I: C)-Induced Alveolar Epithelial Injury by Modulating Redox, Apoptotic, Inflammatory, and Inflammasome Responses.
The MTRNR2L gene family and age-related macular degeneration.
Humanin Attenuates Inflammatory Liver Injury and NF-κB Activation During Systemic Hypervirulent Klebsiella pneumoniae Infection.
The MTRNR2L gene family and age-related macular degeneration.
Low Dose Ketamine Preconditions Astrocyte Mitochondria to Achieve Antidepressant Efficacy via Adenosine, Humanin, and Melatonin Upregulation and Efflux.
S14G-humanin attenuates renal ischaemia-reperfusion injury, potentially through activation of STAT3 and ERK1/2 signalling pathways in rats.
AGEs-RAGE Axis and Mitochondrial-Derived Peptides in Advanced Chronic Kidney Disease: Interconnected Pathways Beyond Inflammation and Nutrition.
Dihydroquercetin alleviates mitochondrial dysfunction and inhibits NLRP3-mediated pyroptosis in primary hepatocytes from chronic liver failure patients.
Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.
Network Topology and Interactomic Analysis Reveal the Regulatory Framework of the Humanin Protein Family (MTRNR2Lx Class).
Humanin
Neuroprotective Action of Humanin and Humanin Analogues: Research Findings and Perspectives
Humanin and the Receptors for Humanin
Figure 2: Diagram of the effects of mitochondrial peptides MOTS-c and humanin.
Humanin
Humanin: A Novel Therapeutic Target in Prostate Cancer
Inactive C8A-humanin analog is as stable as a potent S14G-humanin analog
Ανάπτυξη συνθετικών πεπτιδίων και αντισωμάτων για τη μελέτη του νευροπροστατευτικού 24 - πεπτιδίου ουμανίνη ( Humanin )
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Renal transplantation is the most effective renal replacement therapy for patients with end-stage renal disease. Ischemia-reperfusion injury may adversely affect graft function and long-term outcomes. Ferroptosis has recently emerged as a potential mechanism involved in ischemia-reperfusion injury, while...
* Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead...
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment. Patients will be randomized into two groups: combined exercise (high-intensity aerobic resistance + strength training) and control...
The goal of this observational study is to explore the value of Humanin for early diagnosis and short-term prognosis of AKI patients after heart transplantation. The main question it aims to answer are:whether Humanin can be a novel...
The goal of this observational study is to assess the clinical value of humanin in acute kidney injury. The main questions it aims to answer are:whether Humanin can be a novel marker for predicting AKI Researchers will compare...
1. To investigate the circulating concentrations of phoenixin and their associations with BMI, the concentrations of sex hormones including (LH), (FSH), (E2), (P4), (TT) and steroid hormones enzyme in PCOS patients. 2. To detect the expression PNX and...
Objective of the study is to clarify humanin-like peptide concentration in myocard tissue and in blood and to study if its concentration level is related to early complication occurrence and frequency after cardiac operation. Hypothesis of the study...
Ramazan SB, Turan B, Turkkol A, Çalişkan ŞG, Oyur ME, Alici MH, Kolac UK
Moosa A, Wang JJ, DeAngelis MM, Zhang SX
Shen A, Wang P, Wu B, Fu H, Zeng Y, Zhang C, Wu P, Zhang X, Zhang H, Xu H, Wang L
Anderson G
Zhong Y, Haishaer D, Cai W, Lin L, Guo Z, Pan Y, Tang X, You W, Fu Y, Ou Q
Li CY, Zhang NN, Yang YL, Zhao SS, Xu XF, Cao PY
Kurian GA
Abueid L, Torun AF, Golal E, Acar N, Basrali F
Shaji V, Jain R, Puthumadathil N, Jana K, T S V, Kleinekathöfer U, Chattopadhyay K, Mahendran KR
Suliman ME, Rahman A, Qureshi AR, Barany P, Stenvinkel P, Kublickiene K, Lindholm B
Ayubi N, Wibawa JC, Kurnaz M, Komaini A
Moosa A, Wang JJ, DeAngelis MM, Zhang SX · Frontiers in immunology
Shen A, Wang P, Wu B, Fu H, Zeng Y, Zhang C, Wu P, Zhang X, Zhang H, Xu H, Wang L · American journal of translational research
Zhong Y, Haishaer D, Cai W, Lin L, Guo Z, Pan Y, Tang X, You W, Fu Y, Ou Q · Pathogens
Anderson G · Alpha psychiatry
Horwath O, Corell L, Wan J, Hjalmarsson E, Starck J, Reitzner SM, Norrbom J, Fernandez-Gonzalo R, Kvist O, Cohen P, von Walden F, Edman S · Experimental physiology
Abueid L, Torun AF, Golal E, Acar N, Basrali F · Experimental physiology
Suliman ME, Rahman A, Qureshi AR, Barany P, Stenvinkel P, Kublickiene K, Lindholm B · Antioxidants (Basel, Switzerland)
Shahzaib M, Aprile D, Laporta G, Galderisi U, Colonna G · Biomolecules
Humanin is a 24-mer peptide first reported in the early 2000s as a new neuroprotective/cytoprotective factor rescuing neuronal cells from death induced by various Alzheimer’s disease-associated insults. Nowadays it is known that humanin belongs to the novel class...
· Qeios
TSUTOMU ARAKAWA, TAKAKO NIIKURA, YOSHIKO KITA · Spandidos Publications
Masaaki Matsuoka, Yuichi Hashimoto · Springer Science and Business Media LLC
Pinchas Cohen · Defense Technical Information Center
· Wiley
· PeerJ
Η ουμανίνη (humanin ή HN, MAPRGFSCLLLLTSEIDLPVKRRA) είναι ένα 24-πεπτίδιο που ανακαλύφθηκε το 2001 ως το προϊόν έκφρασης ενός γονιδίου με νευροπροστατευτική δράση. Συγκεκριμένα, η ΗΝ βρέθηκε να αποτρέπει in vitro το θάνατο των νευρικών κυττάρων που προκαλείται από...
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