Research context
A ghrelin-receptor agonist studied in endocrine and growth-hormone research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Growth-hormone research
Ipamorelin
A ghrelin-receptor agonist studied in endocrine and growth-hormone research.
35 connected records35 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Coutinho LFD, DE Oliveira Neves LF, Camilo RP
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
pubmed 2026
Villegas Meza AD, Nocek M, Mitchell BC, Lizarraga M, DeFoor MT, Ruzbarsky JJ, Huard J, Philippon MJ
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.
pubmed
Renke G, Chinellato L
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives.
pubmed
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
pubmed 2026
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M · Frontiers in endocrinology
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
pmc 2026
Mendias CL, Awan TM
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
pubmed 2026
The purpose of this study is to determine if ipamorelin is safe and effective in the management of post-operative ileus.
Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus
clinicaltrials 2008
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder (PTSD) and traumatic brain injury-related cognitive symptoms among Special Operations Forces (SOF) combat veterans.
Trifecta Research Study
clinicaltrials 2026
Post-operative administration of ipamorelin is expected to reduce time to recovery of Gastrointestinal (GI) function in patients who have undergone partial small and/or large bowel resection.
Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function
clinicaltrials 2011
N Mohammadi E, Louwies T, Pietra C, Northrup SR, Greenwood-Van Meerveld B · Journal of experimental pharmacology
Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics.
pmc 2026
Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI · Translational andrology and urology
Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.
pmc 2020
Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C · Journal of experimental pharmacology
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus.
pmc 2026
Johansen PB, Segev Y, Landau D, Phillip M, Flyvbjerg A · Experimental diabesity research
Growth hormone (GH) hypersecretion and GH receptor resistance in streptozotocin diabetic mice in response to a GH secretagogue.
pmc
· Qeios
Ipamorelin
crossref 2020
John Rudd · Morressier
18 / THE GHRELIN AGONISTS, ANAMORELIN AND IPAMORELIN, ANTAGONIZE CISPLATIN-INDUCED ANOREXIA AND EMESIS IN THE FERRET
crossref 2018
David E. Beck, W. Brian Sweeney, Martin D. McCarter · Springer Science and Business Media LLC
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients
crossref 2014
Claudio Pietra, John Friend, Beverley Greenwood-Van Meerveld · Elsevier BV
Preclinical Pharmacological Profile of Ipamorelin a Novel Gastroprokinetic for Intestinal Dysmotility
crossref 2011
P. B. JOHANSEN · Informa UK Limited
Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption
crossref 1998
Lars Müller, Kjeld Madsen, Christian Foged · Wiley
14C‐labelling of ipamorelin, a growth hormone secretagogue
crossref 1998
Beverley Greenwood-Van Meerveld, Karl Tyler, Ehsan Mohammadi, Claudio Peitra · Informa UK Limited
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
crossref 2012
MH Rasmussen, B Soogaar, L Ynddal, L Groes, L Helmgaard, L Nordholm · Elsevier BV
Ipamorelin — A novel very potent growth hormone secretagogue
crossref 1998
Kirsten Raun, Birgit Sehested Hansen, Niklas Dyrby Johansen, Henning Thøgersen, K. Madsen, Michael Ankersen et al. · European Journal of Endocrinology · 99 citations
Ipamorelin, the first selective growth hormone secretagogue
openalex 1998
Kalina M. Venkova, William Mann, Richard L. Nelson, Beverley Greenwood–Van Meerveld · Journal of Pharmacology and Experimental Therapeutics · 33 citations
Efficacy of Ipamorelin, a Novel Ghrelin Mimetic, in a Rodent Model of Postoperative Ileus
openalex 2009
Michael Ankersen, Nils Langeland Johansen, Kjeld Madsen, Birgit Sehested Hansen, Kirsten Raun, Karin Kramer Nielsen et al. · Journal of Medicinal Chemistry · 34 citations
A New Series of Highly Potent Growth Hormone-Releasing Peptides Derived from Ipamorelin
openalex 1998
Jogarao V. S. Gobburu, Henrik Agersø, William J. Jusko, Lars Ynddal · Pharmaceutical Research · 28 citations
Pharmacokinetic-Pharmacodynamic Modeling of Ipamorelin, a Growth Hormone Releasing Peptide, in Human Volunteers
openalex 1999
E. N. Semenistaya, Irina Zvereva, Andreas Thomas, Mario Thevis, Grigory I. Krotov, Grigory M. Rodchenkov · Drug Testing and Analysis · 49 citations
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
openalex 2015
Johan Svensson, Sabrina Lall, Suzanne L. Dickson, B.-Å. Bengtsson, John Rømer, Ian Ahnfelt-Rønne et al. · Journal of Endocrinology · 30 citations
The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats
openalex 2000
Peter Johansen, Jette Nowak, Christian Baaner Skjærbæk, Allan Flyvbjerg, Troels Torp Andreassen, Michael Wilken et al. · Growth Hormone & IGF Research · 24 citations
Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats
openalex 1999
On behalf of the Ipamorelin 201 Study Group, David E. Beck, W. Brian Sweeney, Martin D. McCarter · International Journal of Colorectal Disease · 28 citations
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients
openalex 2014
Tewari K, Liu TP, Im C, Hamad C, Petrigliano F, Cheung EC, Kremen TJ Jr
Peptide Supplements and Their Therapeutic Applications in Sports Medicine.
pubmed
Shah A, Aria F, Gagnier J, Wasserstein D · Orthopaedic Journal of Sports Medicine
Paper 32. Performance & Promises: A Social Media Review of Alleged Indications, Risks and Usage of “Peptides” in Musculoskeletal Health.
pmc 2026
Mavrych V, Shypilova I, Bolgova O
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
pubmed 2026
Rahman OF, Lee SJ, Seeds WA
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pubmed
Mavrych V, Shypilova I, Bolgova O · Frontiers in aging
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
pmc 2026
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pmc
Connected data hub
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Clinical Trial
3 recordsclinicaltrialsAdmin reviewed
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder (PTSD) and traumatic brain injury-related cognitive symptoms among Special Operations Forces (SOF) combat veterans.
clinicaltrialsAdmin reviewed
Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function
Post-operative administration of ipamorelin is expected to reduce time to recovery of Gastrointestinal (GI) function in patients who have undergone partial small and/or large bowel resection.
clinicaltrialsAdmin reviewed
Safety and Efficacy of Ipamorelin for Management of Post-Operative Ileus
The purpose of this study is to determine if ipamorelin is safe and effective in the management of post-operative ileus.
Open Access Article
8 recordspmcAutomated import
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M · Frontiers in endocrinology
pmcAutomated import
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Mavrych V, Shypilova I, Bolgova O · Frontiers in aging
pmcAutomated import
Attenuation of Visceral and Somatic Nociception by Ghrelin Mimetics.
N Mohammadi E, Louwies T, Pietra C, Northrup SR, Greenwood-Van Meerveld B · Journal of experimental pharmacology
pmcAutomated import
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus.
Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C · Journal of experimental pharmacology
pmcAutomated import
Paper 32. Performance & Promises: A Social Media Review of Alleged Indications, Risks and Usage of “Peptides” in Musculoskeletal Health.
Shah A, Aria F, Gagnier J, Wasserstein D · Orthopaedic Journal of Sports Medicine
pmcAutomated import
Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.
Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI · Translational andrology and urology
pmcAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
pmcAutomated import
Growth hormone (GH) hypersecretion and GH receptor resistance in streptozotocin diabetic mice in response to a GH secretagogue.
Johansen PB, Segev Y, Landau D, Phillip M, Flyvbjerg A · Experimental diabesity research
Publication
8 recordspubmedAutomated import
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, RuchaŁa M
pubmedAutomated import
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Mavrych V, Shypilova I, Bolgova O
pubmedAutomated import
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
Mendias CL, Awan TM
pubmedAutomated import
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
Coutinho LFD, DE Oliveira Neves LF, Camilo RP
pubmedAutomated import
Peptide Supplements and Their Therapeutic Applications in Sports Medicine.
Tewari K, Liu TP, Im C, Hamad C, Petrigliano F, Cheung EC, Kremen TJ Jr
pubmedAutomated import
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.
Villegas Meza AD, Nocek M, Mitchell BC, Lizarraga M, DeFoor MT, Ruzbarsky JJ, Huard J, Philippon MJ
pubmedAutomated import
Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives.
Renke G, Chinellato L
pubmedAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA
Scholarly Work
8 recordscrossrefAutomated import
Ipamorelin
· Qeios
crossrefAutomated import
18 / THE GHRELIN AGONISTS, ANAMORELIN AND IPAMORELIN, ANTAGONIZE CISPLATIN-INDUCED ANOREXIA AND EMESIS IN THE FERRET
John Rudd · Morressier
crossrefAutomated import
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients
David E. Beck, W. Brian Sweeney, Martin D. McCarter · Springer Science and Business Media LLC
crossrefAutomated import
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
Beverley Greenwood-Van Meerveld, Karl Tyler, Ehsan Mohammadi, Claudio Peitra · Informa UK Limited
crossrefAutomated import
Preclinical Pharmacological Profile of Ipamorelin a Novel Gastroprokinetic for Intestinal Dysmotility
Claudio Pietra, John Friend, Beverley Greenwood-Van Meerveld · Elsevier BV
crossrefAutomated import
14C‐labelling of ipamorelin, a growth hormone secretagogue
Lars Müller, Kjeld Madsen, Christian Foged · Wiley
crossrefAutomated import
Ipamorelin — A novel very potent growth hormone secretagogue
MH Rasmussen, B Soogaar, L Ynddal, L Groes, L Helmgaard, L Nordholm · Elsevier BV
crossrefAutomated import
Pharmacokinetic evaluation of ipamorelin and other peptidyl growth hormone secretagogues with emphasis on nasal absorption
P. B. JOHANSEN · Informa UK Limited
Article
8 recordsopenalexAutomated import
Determination of growth hormone releasing peptides metabolites in human urine after nasal administration of GHRP‐1, GHRP‐2, GHRP‐6, Hexarelin, and Ipamorelin
E. N. Semenistaya, Irina Zvereva, Andreas Thomas, Mario Thevis, Grigory I. Krotov, Grigory M. Rodchenkov · Drug Testing and Analysis · 49 citations
openalexAutomated import
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients
On behalf of the Ipamorelin 201 Study Group, David E. Beck, W. Brian Sweeney, Martin D. McCarter · International Journal of Colorectal Disease · 28 citations
openalexAutomated import
Efficacy of Ipamorelin, a Novel Ghrelin Mimetic, in a Rodent Model of Postoperative Ileus
Kalina M. Venkova, William Mann, Richard L. Nelson, Beverley Greenwood–Van Meerveld · Journal of Pharmacology and Experimental Therapeutics · 33 citations
openalexAutomated import
The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats
Johan Svensson, Sabrina Lall, Suzanne L. Dickson, B.-Å. Bengtsson, John Rømer, Ian Ahnfelt-Rønne et al. · Journal of Endocrinology · 30 citations
openalexAutomated import
Pharmacokinetic-Pharmacodynamic Modeling of Ipamorelin, a Growth Hormone Releasing Peptide, in Human Volunteers
Jogarao V. S. Gobburu, Henrik Agersø, William J. Jusko, Lars Ynddal · Pharmaceutical Research · 28 citations
openalexAutomated import
Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats
Peter Johansen, Jette Nowak, Christian Baaner Skjærbæk, Allan Flyvbjerg, Troels Torp Andreassen, Michael Wilken et al. · Growth Hormone & IGF Research · 24 citations
openalexAutomated import
Ipamorelin, the first selective growth hormone secretagogue
Kirsten Raun, Birgit Sehested Hansen, Niklas Dyrby Johansen, Henning Thøgersen, K. Madsen, Michael Ankersen et al. · European Journal of Endocrinology · 99 citations
openalexAutomated import
A New Series of Highly Potent Growth Hormone-Releasing Peptides Derived from Ipamorelin
Michael Ankersen, Nils Langeland Johansen, Kjeld Madsen, Birgit Sehested Hansen, Kirsten Raun, Karin Kramer Nielsen et al. · Journal of Medicinal Chemistry · 34 citations
Live discovery
Latest research signals
Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
Recent PubMed records
Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review.PMID 42862021 · 2026 Sep 30Peptide Supplements and Their Therapeutic Applications in Sports Medicine.PMID 42578445 · 2026 Aug 11The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.PMID 42395176 · 2026Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.PMID 42160466 · 2026 May 1Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future Perspectives.PMID 42123471 · 2026 Apr 27Registered clinical studies
Safety and Efficacy of Ipamorelin for Management of Post-Operative IleusNCT00672074 · COMPLETEDTrifecta Research StudyNCT07717866 · ACTIVE_NOT_RECRUITINGSafety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal FunctionNCT01280344 · COMPLETEDReviewed UniProt records
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