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Inflammation research

KPV

A short alpha-MSH-derived peptide studied in preclinical inflammatory signalling models.

33 connected records33 graded citations0 external identifiers

Research context

A short alpha-MSH-derived peptide studied in preclinical inflammatory signalling models.

Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.

Evidence map

Claims linked to original records.

Evidence levels describe study design. They do not by themselves establish safety or effectiveness.

Not yet classified

An SH, Park JY, Lee SJ

KPV attenuates adipogenesis and lipid metabolism through modulation of ROS-mediated AKT/mTORC1/PPARγ signaling.

pubmed
Not yet classified

Lee JY, Lee J, Jung WK, Je JY, Lee SJ

Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells.

pubmed 2026
Not yet classified

Coutinho LFD, DE Oliveira Neves LF, Camilo RP

A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.

pubmed 2026
Not yet classified

Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

pubmed
Not yet classified

Rodrigues JM, Ferreira Leal AP, Buccini DF, Franco OL

Host defense peptides as a new drug lead to a strategy for inflammatory bowel disease.

pubmed 2025
Not yet classified

Adnan SB, Maarof M, Fauzi MB, Fadilah NIM

Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.

pubmed 2026
Not yet classified

Zeng K, Zhu Y, Han Z, Xiong S, Zhao Y, Xiao Z, Xie Y, Jin S, Dong T, Lan L, Liu W, Du Y, Guan C, Yu X, Song X

NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.

pubmed 2026
Not yet classified

Sung J, Ju SY, Park S, Jung WK, Je JY, Lee SJ

Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.

pubmed 2025
Not yet classified

Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J · Science advances

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

pmc
Not yet classified

Adnan SB, Maarof M, Fauzi MB, Fadilah NIM · International journal of medical sciences

Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.

pmc 2026
Not yet classified

Zhang D, Jiang L, Yu F, Yan P, Liu Y, Wu Y, Yang X · Frontiers in pharmacology

PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS.

pmc 2026
Not yet classified

Marotti V, Xu Y, Bohns Michalowski C, Zhang W, Domingues I, Ameraoui H, Moreels TG, Baatsen P, Van Hul M, Muccioli GG, Cani PD, Alhouayek M, Malfanti A, Beloqui A · Bioactive materials

A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment.

pmc 2024
Not yet classified

Berr AL, Wiese K, Dos Santos G, Koch CM, Anekalla KR, Kidd M, Davis JM, Cheng Y, Hu YS, Ridge KM · Oncogene

Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.

pmc 2023
Not yet classified

Songok AC, Panta P, Doerrler WT, Macnaughtan MA, Taylor CM · PloS one

Structural modification of the tripeptide KPV by reductive "glycoalkylation" of the lysine residue.

pmc 2026
Not yet classified

Xiao B, Xu Z, Viennois E, Zhang Y, Zhang Z, Zhang M, Han MK, Kang Y, Merlin D · Molecular therapy : the journal of the American Society of Gene Therapy

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis.

pmc
Not yet classified

Viennois E, Ingersoll SA, Ayyadurai S, Zhao Y, Wang L, Zhang M, Han MK, Garg P, Xiao B, Merlin D · Cellular and molecular gastroenterology and hepatology

Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.

pmc 2016
Not yet classified

· DE GRUYTER

III. Die Tafel der Kategorien der Freiheit (KpV A 117)

crossref 2011
Not yet classified

Walter Frank Pintor Ortiz · Nanyang Technological University

Robotic mirror finishing KPV (key process variable) optimization in the aerospace industry

crossref
Not yet classified

Christoph Bambauer · Verlag Karl Alber

VIII. Die Achtungslehre der KpV als praktische Axiologie

crossref 2011
Not yet classified

· De Gruyter

XXIV. Kapitel: Der moralische Gottesbeweis in der Dialektik der KpV

crossref 1989
Not yet classified

Abstract Using the blackfold approach, we study the classical stability of the KPV (Kachru-Pearson-Verlinde) state of anti-D3 branes at the tip of the Klebanov-Strassler throat. With regards to generic long-wavelength deformations considered, we found no instabilities. We comment on the relation of our results to...

Comments on the stability of the KPV state

crossref 2020
Not yet classified

Helen Raybould · H1 Connect

Faculty Opinions recommendation of PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.

crossref 2008
Not yet classified

Para muitos comentadores a doutrina do fato da razão não pode ser defendida com seriedade pois esta implicaria em uma recaída no dogmatismo. Contudo, pretendemos defender, neste artigo, não só que a teoria do fato da razão está de acordo com os resultados da KrV...

A solução crítica do fato da razão na KpV

crossref 2010
Not yet classified

Abstract In this work, we study the decay of $$ \overline{D3} $$ D 3 ¯ -branes in the setup of Kachru, Pearson, and Verlinde (KPV) at higher order in α′ from the perspective of a nonabelian $$ \overline{D3} $$ D 3 ¯ -brane stack. We...

Higher order corrections to KPV: The nonabelian brane stack perspective

crossref 2024
Not yet classified

Guillaume Dalmasso, Laetitia Charrier‐Hisamuddin, Hang Thi Thu Nguyen, Yutao Yan, Shanthi V. Sitaraman, Didier Merlin · Gastroenterology · 123 citations

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

openalex 2007
Not yet classified

Bo Xiao, Zhigang Xu, Émilie Viennois, Yuchen Zhang, Zhan Zhang, Mingzhen Zhang et al. · Molecular Therapy · 183 citations

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

openalex 2017
Not yet classified

Nicholas A. Engerer, Franklin P. Mills · Solar Energy · 121 citations

KPV: A clear-sky index for photovoltaics

openalex 2014
Not yet classified

Klaus Kannengießer, Christian Maaser, Jan Heidemann, Andreas Luegering, Matthias Ross, Thomas Brzoska et al. · Inflammatory Bowel Diseases · 57 citations

Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

openalex 2007
Not yet classified

Richard J. R. Elliott, Marika Szabo, Mark J. Wagner, Elizabeth Helen Kemp, Sheila MacNeil, John W. Haycock · Journal of Investigative Dermatology · 47 citations

α-Melanocyte-Stimulating Hormone, MSH 11–13 KPV and Adrenocorticotropic Hormone Signalling in Human Keratinocyte Cells

openalex 2004
Not yet classified

Stephen J. Getting, Helgi Birgir Schiöth, Mauro Perretti · Journal of Pharmacology and Experimental Therapeutics · 39 citations

Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides

openalex 2003
Not yet classified

Ying‐Zheng Zhao, Pengpeng Xue, Gaolong Lin, Meng‐Qi Tong, Jiaojiao Yang, Yingying Zhang et al. · Acta Biomaterialia · 38 citations

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon

openalex 2022
Not yet classified

Weifeng Shao, Rui Chen, Gaolong Lin, Kunjie Ran, Yingying Zhang, Jiaojiao Yang et al. · Biomaterials Science · 41 citations

In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis

openalex 2021
Not yet classified

Willis J, Vu N

Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.

pubmed

Connected data hub

Records with source provenance.

Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.

Open Access Article

8 records
pmcAutomated import

Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.

Adnan SB, Maarof M, Fauzi MB, Fadilah NIM · International journal of medical sciences

PMC125953172026-09-27
pmcAutomated import

PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS.

Zhang D, Jiang L, Yu F, Yan P, Liu Y, Wu Y, Yang X · Frontiers in pharmacology

PMC113579422026-09-27
pmcAutomated import

Structural modification of the tripeptide KPV by reductive "glycoalkylation" of the lysine residue.

Songok AC, Panta P, Doerrler WT, Macnaughtan MA, Taylor CM · PloS one

PMC60232332026-09-27
pmcAutomated import

A nanoparticle platform for combined mucosal healing and immunomodulation in inflammatory bowel disease treatment.

Marotti V, Xu Y, Bohns Michalowski C, Zhang W, Domingues I, Ameraoui H, Moreels TG, Baatsen P, Van Hul M, Muccioli GG, Cani PD, Alhouayek M, Malfanti A, Beloqui A · Bioactive materials

PMC105823602024-02-01
pmcAutomated import

Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.

Berr AL, Wiese K, Dos Santos G, Koch CM, Anekalla KR, Kidd M, Davis JM, Cheng Y, Hu YS, Ridge KM · Oncogene

PMC102757602023-06-01
pmcAutomated import

Critical role of PepT1 in promoting colitis-associated cancer and therapeutic benefits of the anti-inflammatory PepT1-mediated tripeptide KPV in a murine model.

Viennois E, Ingersoll SA, Ayyadurai S, Zhao Y, Wang L, Zhang M, Han MK, Garg P, Xiao B, Merlin D · Cellular and molecular gastroenterology and hepatology

PMC49579552016-05-01
pmcAutomated import

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J · Science advances

PMC1280283227 Sep 2026
pmcAutomated import

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis.

Xiao B, Xu Z, Viennois E, Zhang Y, Zhang Z, Zhang M, Han MK, Kang Y, Merlin D · Molecular therapy : the journal of the American Society of Gene Therapy

PMC549880427 Sep 2026

Publication

9 records
pubmedAutomated import

Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.

Adnan SB, Maarof M, Fauzi MB, Fadilah NIM

412095472026-09-27
pubmedAutomated import

A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.

Coutinho LFD, DE Oliveira Neves LF, Camilo RP

418801992026-07-01
pubmedAutomated import

Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells.

Lee JY, Lee J, Jung WK, Je JY, Lee SJ

420648352026-06-01
pubmedAutomated import

NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.

Zeng K, Zhu Y, Han Z, Xiong S, Zhao Y, Xiao Z, Xie Y, Jin S, Dong T, Lan L, Liu W, Du Y, Guan C, Yu X, Song X

409358352026-02-01
pubmedAutomated import

Host defense peptides as a new drug lead to a strategy for inflammatory bowel disease.

Rodrigues JM, Ferreira Leal AP, Buccini DF, Franco OL

412413762025-12-01
pubmedAutomated import

Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.

Sung J, Ju SY, Park S, Jung WK, Je JY, Lee SJ

400734672025-08-01
pubmedAutomated import

Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.

Willis J, Vu N

4275242627 Sep 2026
pubmedAutomated import

KPV attenuates adipogenesis and lipid metabolism through modulation of ROS-mediated AKT/mTORC1/PPARγ signaling.

An SH, Park JY, Lee SJ

4258580327 Sep 2026
pubmedAutomated import

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J

4153378827 Sep 2026

Scholarly Work

8 records
crossrefAutomated import

Higher order corrections to KPV: The nonabelian brane stack perspective

Abstract In this work, we study the decay of $$ \overline{D3} $$ D 3 ¯ -branes in the setup of Kachru, Pearson, and Verlinde (KPV) at higher order in α′ from the perspective of a nonabelian $$ \overline{D3}...

10.1007/jhep07(2024)0752024-07-09
crossrefAutomated import

Comments on the stability of the KPV state

Abstract Using the blackfold approach, we study the classical stability of the KPV (Kachru-Pearson-Verlinde) state of anti-D3 branes at the tip of the Klebanov-Strassler throat. With regards to generic long-wavelength deformations considered, we found no instabilities. We comment...

10.1007/jhep11(2020)0552020-11-01
crossrefAutomated import

III. Die Tafel der Kategorien der Freiheit (KpV A 117)

· DE GRUYTER

10.1515/9783110272338.1962011-09-27
crossrefAutomated import

VIII. Die Achtungslehre der KpV als praktische Axiologie

Christoph Bambauer · Verlag Karl Alber

10.5771/9783495997666-4152011-01-01
crossrefAutomated import

A solução crítica do fato da razão na KpV

Para muitos comentadores a doutrina do fato da razão não pode ser defendida com seriedade pois esta implicaria em uma recaída no dogmatismo. Contudo, pretendemos defender, neste artigo, não só que a teoria do fato da razão está...

10.5380/sk.v8i10.886552010-05-10
crossrefAutomated import

Faculty Opinions recommendation of PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.

Helen Raybould · H1 Connect

10.3410/f.1108420.5644702008-05-10
crossrefAutomated import

XXIV. Kapitel: Der moralische Gottesbeweis in der Dialektik der KpV

· De Gruyter

10.1515/9783110846331.3971989-11-01
crossrefAutomated import

Robotic mirror finishing KPV (key process variable) optimization in the aerospace industry

Walter Frank Pintor Ortiz · Nanyang Technological University

10.32657/10356/6549727 Sep 2026

Article

8 records
openalexAutomated import

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon

Ying‐Zheng Zhao, Pengpeng Xue, Gaolong Lin, Meng‐Qi Tong, Jiaojiao Yang, Yingying Zhang et al. · Acta Biomaterialia · 38 citations

10.1016/j.actbio.2022.02.0392022-03-01
openalexAutomated import

In situ mucoadhesive hydrogel capturing tripeptide KPV: the anti-inflammatory, antibacterial and repairing effect on chemotherapy-induced oral mucositis

Weifeng Shao, Rui Chen, Gaolong Lin, Kunjie Ran, Yingying Zhang, Jiaojiao Yang et al. · Biomaterials Science · 41 citations

10.1039/d1bm01466h2021-11-18
openalexAutomated import

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis

Bo Xiao, Zhigang Xu, Émilie Viennois, Yuchen Zhang, Zhan Zhang, Mingzhen Zhang et al. · Molecular Therapy · 183 citations

10.1016/j.ymthe.2016.11.0202017-01-28
openalexAutomated import

KPV: A clear-sky index for photovoltaics

Nicholas A. Engerer, Franklin P. Mills · Solar Energy · 121 citations

10.1016/j.solener.2014.04.0192014-05-21
openalexAutomated import

Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

Klaus Kannengießer, Christian Maaser, Jan Heidemann, Andreas Luegering, Matthias Ross, Thomas Brzoska et al. · Inflammatory Bowel Diseases · 57 citations

10.1002/ibd.203342007-12-18
openalexAutomated import

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

Guillaume Dalmasso, Laetitia Charrier‐Hisamuddin, Hang Thi Thu Nguyen, Yutao Yan, Shanthi V. Sitaraman, Didier Merlin · Gastroenterology · 123 citations

10.1053/j.gastro.2007.10.0262007-11-26
openalexAutomated import

α-Melanocyte-Stimulating Hormone, MSH 11–13 KPV and Adrenocorticotropic Hormone Signalling in Human Keratinocyte Cells

Richard J. R. Elliott, Marika Szabo, Mark J. Wagner, Elizabeth Helen Kemp, Sheila MacNeil, John W. Haycock · Journal of Investigative Dermatology · 47 citations

10.1111/j.0022-202x.2004.22404.x2004-04-01
openalexAutomated import

Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) α-Melanocyte-Stimulating Hormone Peptides

Stephen J. Getting, Helgi Birgir Schiöth, Mauro Perretti · Journal of Pharmacology and Experimental Therapeutics · 39 citations

10.1124/jpet.103.0516232003-07-18
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