Research context
A peptide hormone used in clinical care and behavioural neuroscience research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Neuropeptide
Oxytocin Acetate
A peptide hormone used in clinical care and behavioural neuroscience research.
30 connected records29 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Amin N, Hussein AB, Ye Q, Chen S, Wu F, Yuan X, Abbasi IN, Sundus J, Hu Z, Fang M
Combination of rTMS and oxytocin agonist attenuate depression-like behavior after postpartum depression in mice.
pubmed
Carbonari A, Burgio M, Frattina L, Ceci E, Sciannamblo M, Ricci P, Cicirelli V, Rizzo A
Oxytocin, prostaglandin F2(α), and scopolamine for uterine involution of dairy cows.
pubmed 2026
Siricilla S, Hansen CJ, Rogers JH, De D, Simpson CL, Waterson AG, Sulikowski GA, Crockett SL, Boatwright N, Reese J, Paria BC, Newton J, Herington JL
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
pubmed 2023
Chen TH, Misra TK, Liu CY
Capillary electrochromatographic separation of peptides using a macrocyclic polyamine for molecular recognition.
pubmed 2008
Weston GC, Cann L, Rogers PA
Myometrial microvascular endothelial cells express oxytocin receptor.
pubmed 2003
Chen K, Chang LS
Oxytocinergic neurotransmission at the hippocampus in the central neural regulation of penile erection in the rat.
pubmed 2001
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
clinicaltrials 2022
This is an open-label, pilot study, to characterize oxytocin response to a single dose of oral Estrogen-progestin in patients with arginine-vasopressin deficiency compared to healthy controls. The association between oxytocin levels and measures of psychopathology (i.e., anxiety and depression) and quality of life across groups...
Identifying Oxytocin Deficiency in Adults With Pituitary Disease
clinicaltrials 2024
An open-labeled, interventional pilot trial, 10 youth with AVP-D and 10 PD matched for age, sex, and BMI will be recruited from Pediatric Endocrinology and Neuroendocrinology at Massachusetts General Hospital and in the community. This study tests the hypothesis that oral estrogen/progestin will stimulate endogenous...
Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease
clinicaltrials 2026
The primary objective of this study is to demonstrate the superiority of retosiban to prolong pregnancy in females with spontaneous preterm labor compared with atosiban. This objective is based on the hypothesis that prolonging the time to delivery in the absence of harm may benefit...
A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
clinicaltrials 2014
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg in the same arm and proteinuria \>300...
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
clinicaltrials 2020
This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia
Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
clinicaltrials 2017
Montague Redecke SG, Bell-Hensley A, Yi M, Li S, DeMayo FJ · F&S science
Progesterone receptor isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells.
pmc 2025
Horie N, Kusano K, Yokozeki K, Osada K, Nagayasu H, Shimo T, Murata M · Journal of clinical and experimental dentistry
Improvement in Quality of Life Using an Ethylene-Vinyl Acetate Palatal Obturator in a Patient with Self-Inflicted Nasal Defect and Palatal Perforation.
pmc 2026
Feng B, Guo W, Zhao S, Wang H, Wang X, Zhang K, Song D, Gao P · Frontiers in pharmacology
Linalyl acetate alleviates inflammatory pain via OLFR482 activation in the mouse anterior cingulate cortex.
pmc 2026
Biliński K, Wiśniewski K, Rafner L, Witko P, Gaweł-Dąbrowska D · Nutrients
Travel-Induced Circadian and Microbiota Disturbances: Implications for Athlete Health and Performance: A Narrative Review.
pmc
Fu H, Li J, Miao R, Mai Z, Lu Y, Xiao Y, Kuang L, Guo Q · Frontiers in microbiology
Maternal Taishan Panshi San supplementation is associated with improved foal growth performance, accompanied by alterations in gut microbiota and metabolic profiles.
pmc 2026
Arif A, Zahoor N, Sadiq A, Sohail T, Tang M, Dong L, Tang J, Khan SZ, Dai G · Veterinary sciences
Dose-Dependent Effects of Selenium Methionine Supplementation on Functional, Structural, and Physiological Characteristics of Rooster Semen During Liquid Storage at 25 °C.
pmc
Elshamy YS, Holland LA, Corley EL · Analytical chemistry
Capillary Electrophoresis Mass Spectrometry Interfacing via Multifunctional Vibrating Sharp Edge Ionization Spray for the Simultaneous Delivery of an Auxiliary Flow, Analyte Mixing, and Fluid Nebulization.
pmc
Tarhriz V, Xia H, Patel A, Eivazi M, Scarborough A, Miao K, Mir H, Abkhooie L, Mauvais-Jarvis F, Lazartigues E · Hypertension (Dallas, Tex. : 1979)
Sex-Specific Exosome Cargo Reveals Potential New Mechanisms of Salt-Sensitive Hypertension.
pmc 2026
G. Wang, R. B. Miller, L. Melendez, R. Jacobus · Informa UK Limited
A Stability-Indicating HPLC Method for the Determination of Oxytocin Acetate in Oxytocin Injection, USP, Synthetic
crossref 1997
AbstractOxytocin is a cyclic nonapeptide used to induce labor and prevent bleeding after childbirth. Due to its instability, storage and transport of oxytocin formulations can be problematic in hot/tropical climates. The aim of this study was to investigate the effect of trehalose and select antioxidants...
The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stability
crossref 2021
WILLIAM W. THATCHER, H. ALLEN TUCKER · The Endocrine Society
Lactational Performance of Rats Injected with Oxytocin, Cortisol-21-acetate, Prolactin and Growth Hormone During Prolonged Lactation
crossref 1970
STEFANIA DRABAREK, VINCENT DU VIGNEAUD · Elsevier
SYNTHESIS OF 2-d-TYROSINE-OXYTOCIN AND 2-d-TYROSINE-DEAMINO-OXYTOCIN, DIASTEREOISOMERS OF OXYTOCIN AND DEAMINO-OXYTOCIN
crossref 1966
· U.S. Pharmacopeial Convention
Oxytocin
crossref
· U.S. Pharmacopeial Convention
Oxytocin
crossref
· Royal Pharmaceutical Society
oxytocin
crossref
Nan WU, Yan-Jie SU · China Science Publishing & Media Ltd.
Oxytocin, Oxytocin Receptor Genotypes and Social Adaptive Behavior
crossref 2013
Oxytocin (9-amino acid peptide) hormone is a member of the G-protein coupled receptor family. It regulates a range of physiologic actions in mammals other than assisting parturition and lactation functions. Evidence indicates that oxytocin alters lipids, protein, and sugar metabolism through various ways including modulation...
Oxytocin as a Metabolic Modulator
crossref 2021
Connected data hub
Records with source provenance.
Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.
Regulatory Label
1 recordsopenfdaAdmin reviewed
Emotional Eating — Dosage and Administration
DIRECTIONS: 3-10 drops under the tongue, 3 times a day or as directed by a health professional. Consult a physician for use in children under 12 years of age.
Open Access Article
8 recordspmcAutomated import
Linalyl acetate alleviates inflammatory pain via OLFR482 activation in the mouse anterior cingulate cortex.
Feng B, Guo W, Zhao S, Wang H, Wang X, Zhang K, Song D, Gao P · Frontiers in pharmacology
pmcAutomated import
Maternal Taishan Panshi San supplementation is associated with improved foal growth performance, accompanied by alterations in gut microbiota and metabolic profiles.
Fu H, Li J, Miao R, Mai Z, Lu Y, Xiao Y, Kuang L, Guo Q · Frontiers in microbiology
pmcAutomated import
Improvement in Quality of Life Using an Ethylene-Vinyl Acetate Palatal Obturator in a Patient with Self-Inflicted Nasal Defect and Palatal Perforation.
Horie N, Kusano K, Yokozeki K, Osada K, Nagayasu H, Shimo T, Murata M · Journal of clinical and experimental dentistry
pmcAutomated import
Sex-Specific Exosome Cargo Reveals Potential New Mechanisms of Salt-Sensitive Hypertension.
Tarhriz V, Xia H, Patel A, Eivazi M, Scarborough A, Miao K, Mir H, Abkhooie L, Mauvais-Jarvis F, Lazartigues E · Hypertension (Dallas, Tex. : 1979)
pmcAutomated import
Progesterone receptor isoform modulation via enhancer activation regulates progesterone signaling in endometrial stromal cells.
Montague Redecke SG, Bell-Hensley A, Yi M, Li S, DeMayo FJ · F&S science
pmcAutomated import
Travel-Induced Circadian and Microbiota Disturbances: Implications for Athlete Health and Performance: A Narrative Review.
Biliński K, Wiśniewski K, Rafner L, Witko P, Gaweł-Dąbrowska D · Nutrients
pmcAutomated import
Dose-Dependent Effects of Selenium Methionine Supplementation on Functional, Structural, and Physiological Characteristics of Rooster Semen During Liquid Storage at 25 °C.
Arif A, Zahoor N, Sadiq A, Sohail T, Tang M, Dong L, Tang J, Khan SZ, Dai G · Veterinary sciences
pmcAutomated import
Capillary Electrophoresis Mass Spectrometry Interfacing via Multifunctional Vibrating Sharp Edge Ionization Spray for the Simultaneous Delivery of an Auxiliary Flow, Analyte Mixing, and Fluid Nebulization.
Elshamy YS, Holland LA, Corley EL · Analytical chemistry
Publication
6 recordspubmedAutomated import
Oxytocin, prostaglandin F2(α), and scopolamine for uterine involution of dairy cows.
Carbonari A, Burgio M, Frattina L, Ceci E, Sciannamblo M, Ricci P, Cicirelli V, Rizzo A
pubmedAutomated import
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
Siricilla S, Hansen CJ, Rogers JH, De D, Simpson CL, Waterson AG, Sulikowski GA, Crockett SL, Boatwright N, Reese J, Paria BC, Newton J, Herington JL
pubmedAutomated import
Capillary electrochromatographic separation of peptides using a macrocyclic polyamine for molecular recognition.
Chen TH, Misra TK, Liu CY
pubmedAutomated import
Myometrial microvascular endothelial cells express oxytocin receptor.
Weston GC, Cann L, Rogers PA
pubmedAutomated import
Oxytocinergic neurotransmission at the hippocampus in the central neural regulation of penile erection in the rat.
Chen K, Chang LS
pubmedAutomated import
Combination of rTMS and oxytocin agonist attenuate depression-like behavior after postpartum depression in mice.
Amin N, Hussein AB, Ye Q, Chen S, Wu F, Yuan X, Abbasi IN, Sundus J, Hu Z, Fang M
Clinical Trial
6 recordsclinicaltrialsAutomated import
Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease
An open-labeled, interventional pilot trial, 10 youth with AVP-D and 10 PD matched for age, sex, and BMI will be recruited from Pediatric Endocrinology and Neuroendocrinology at Massachusetts General Hospital and in the community. This study tests the...
clinicaltrialsAutomated import
Identifying Oxytocin Deficiency in Adults With Pituitary Disease
This is an open-label, pilot study, to characterize oxytocin response to a single dose of oral Estrogen-progestin in patients with arginine-vasopressin deficiency compared to healthy controls. The association between oxytocin levels and measures of psychopathology (i.e., anxiety and...
clinicaltrialsAutomated import
Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia
clinicaltrialsAutomated import
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg...
clinicaltrialsAutomated import
Combined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean Delivery
This study will compare between combination of colloids/crystalloids and crystalloids in women with preeclampsia undergoing elective cesarean delivery under spinal anesthesia
clinicaltrialsAutomated import
A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
The primary objective of this study is to demonstrate the superiority of retosiban to prolong pregnancy in females with spontaneous preterm labor compared with atosiban. This objective is based on the hypothesis that prolonging the time to delivery...
Scholarly Work
9 recordscrossrefAutomated import
Oxytocin as a Metabolic Modulator
Oxytocin (9-amino acid peptide) hormone is a member of the G-protein coupled receptor family. It regulates a range of physiologic actions in mammals other than assisting parturition and lactation functions. Evidence indicates that oxytocin alters lipids, protein, and...
crossrefAutomated import
The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stability
AbstractOxytocin is a cyclic nonapeptide used to induce labor and prevent bleeding after childbirth. Due to its instability, storage and transport of oxytocin formulations can be problematic in hot/tropical climates. The aim of this study was to investigate...
crossrefAutomated import
Oxytocin, Oxytocin Receptor Genotypes and Social Adaptive Behavior
Nan WU, Yan-Jie SU · China Science Publishing & Media Ltd.
crossrefAutomated import
A Stability-Indicating HPLC Method for the Determination of Oxytocin Acetate in Oxytocin Injection, USP, Synthetic
G. Wang, R. B. Miller, L. Melendez, R. Jacobus · Informa UK Limited
crossrefAutomated import
Lactational Performance of Rats Injected with Oxytocin, Cortisol-21-acetate, Prolactin and Growth Hormone During Prolonged Lactation
WILLIAM W. THATCHER, H. ALLEN TUCKER · The Endocrine Society
crossrefAutomated import
SYNTHESIS OF 2-d-TYROSINE-OXYTOCIN AND 2-d-TYROSINE-DEAMINO-OXYTOCIN, DIASTEREOISOMERS OF OXYTOCIN AND DEAMINO-OXYTOCIN
STEFANIA DRABAREK, VINCENT DU VIGNEAUD · Elsevier
crossrefAutomated import
Oxytocin
· U.S. Pharmacopeial Convention
crossrefAutomated import
Oxytocin
· U.S. Pharmacopeial Convention
crossrefAutomated import
oxytocin
· Royal Pharmaceutical Society
Live discovery
Latest research signals
Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
Recent PubMed records
Combination of rTMS and oxytocin agonist attenuate depression-like behavior after postpartum depression in mice.PMID 39832612 · 2025 Mar 15Oxytocin, prostaglandin F2(α), and scopolamine for uterine involution of dairy cows.PMID 38756512 · 2024Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.PMID 37536638 · 2023 SepCapillary electrochromatographic separation of peptides using a macrocyclic polyamine for molecular recognition.PMID 18383032 · 2008 AprMyometrial microvascular endothelial cells express oxytocin receptor.PMID 12618159 · 2003 FebRegistered clinical studies
Changes in Cardiac Output During Cesarean Delivery Under Spinal AnesthesiaNCT05269537 · COMPLETEDCombined Colloids And Crystalloids Versus Crystalloids in Women With Preeclampsia Undergoing Cesarean DeliveryNCT03252496 · COMPLETEDA Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm LabourNCT02292771 · TERMINATEDReviewed UniProt records
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