Research context
A short peptide studied in preclinical neurobiology and ageing research.
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Bioregulator research
Pinealon
A short peptide studied in preclinical neurobiology and ageing research.
24 connected records24 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Myakotnykh VS, Torgashov MN, Egorin KV, Meshchaninov VN, Gavrilov VI, Borovkova TA, Zvezdina EM, Verzhbitskaya TY, Tkachenko EL
[Comparative analysis of different methods of geroprotective].
pubmed 2026
Meshchaninov VN, Tkachenko EL, Zharkov SV, Gavrilov IV, Katyreva IuE
[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].
pubmed 2026
Mendzheritsky AM, Karantysh GV, Ryzhak GA, Prokofiev VN
[Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia].
pubmed 2026
Mendzheritskiĭ AM, Karantysh GV, Ryzhak GA, Dem'ianenko SV
[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
pubmed 2026
Mendzheritski AM, Karantysh GV, Abramchuk VA, Ryzhak GA
[Effect of peptide geroprotectors on the navigation system learning and caspase-3 in brain structures in rats of different age].
pubmed 2026
Umnov RS, Lin'kova NS, Khavinson VKh
[Neuroprotective effects of peptides bioregulators in people of various age].
pubmed 2026
Nazimko VA, Morgul' EV, Petrova OA, Sheĭkhova RG, Kozina LS, Savenko MA, Lysenko DS
[Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades].
pubmed 2026
Arutjunyan A, Kozina L, Stvolinskiy S, Bulygina Y, Mashkina A, Khavinson V · International journal of clinical and experimental medicine
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.
pmc 2026
Tamara Kuznetsova, Inna Golubeva, Vladimir Khavinson · LCC MAKS Press
PINEALON - PEPTIDE REGULATION OF COGNITIVE ABILITIES OF MACAQUES
crossref 2022
The synthetic tripeptide pinealon (Glu-Asp-Arg) demonstrates dose-dependent restriction of reactive oxygen species (ROS) accumulation in cerebellar granule cells, neutrophils, and pheochromocytoma (PC12) cells, induced by oxidative stress stimulated by receptor-dependent or -independent processes. At the same time, pinealon decreases necrotic cell death measured by the...
Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes
crossref 2011
A. V. Korenevskii, A. V. Arutyunyan, Yu. P. Milyutina, I. V. Zaloznyaya, L. S. Kozina · Pleiades Publishing Ltd
Pinealon corrects hyperhomocysteinemia-induced disturbances of the diurnal dynamics of hypothalamic norepinephrine content in female rats
crossref 2014
G. V. Karantysh, M. P. Fomenko, A. M. Menzheritskii, V. N. Prokof’ev, G. A. Ryzhak, E. V. Butenko · Pleiades Publishing Ltd
Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes
crossref 2020
The article presents an analysis of the effect of pinealon on free radical processes and the level of expression of the SOD1, GPX4 and GSR genes in the rat hippocampus in a model of streptozotocininduced diabetes (type I diabetes mellitus). It has been established that...
INFLUENCE OF PINEALON ON EXPRESSION OF GENES OF PRO- AND ANTIOXIDANT ENZYMES AND FREE RADICAL PROCESSES IN RATS IN THE MODEL OF SUGAR DIABETES
crossref 2020
Tamara G. Kuznetsova, Inna Y. Golubeva, Svetlana V. Trofimova, V. Khavinson, Vyacheslav T. Shuvaev · Moscow University Press
The influence of the Pinealon tripeptide on the rehabilitation of cognitive functions in the aging process using the example of rhesus monkeys (Macaca mulatta)
crossref 2019
Alexander V. Arutjunyan, Lyudmila S. Kozina, Sergey Stvolinskiy, Yelena Bulygina, Anna P. Mashkina, Vladimir Khavinson · PubMed · 27 citations
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.
openalex 2012
V. Khavinson, Y. Ribakova, К.Ю. Кулебякин, Elizaveta A. Vladychenskaya, Lyudmila S. Kozina, Alexander V. Arutjunyan et al. · Rejuvenation Research · 17 citations
Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes
openalex 2011
А. В. Кореневский, Aleksandr Vartanovich Arutyunyan, Yu. P. Milyutina, I. V. Zaloznyaya, Lyudmila S. Kozina · Neurochemical Journal · 3 citations
Pinealon corrects hyperhomocysteinemia-induced disturbances of the diurnal dynamics of hypothalamic norepinephrine content in female rats
openalex 2014
А. М. Менджерицкий, G. V. Karantysh, Galina Anatol’evna Ryzhak, S V Dem'ianenko · PubMed · 3 citations
[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
openalex 2014
Larisa Ivanovna Fedoreyeva, Igor I. Kireev, V. Kh. Khavinson, B. F. Vanyushin · Biochemistry (Moscow) · 65 citations
Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA
openalex 2011
G. V. Karantysh, М. П. Фоменко, A. M. Menzheritskii, В. Н. Прокофьев, Galina Anatol’evna Ryzhak, Elena Viktorovna Butenko · Neurochemical Journal · 1 citations
Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes
openalex 2020
Tamara G. Kuznetsova, Inna Yu. Golubeva, Svetlana Trofimova, V. Khavinson, Шуваев Вячеслав Тимофеевич · Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta Seria XXIII Antropologia) · 3 citations
The influence of the Pinealon tripeptide on the rehabilitation of cognitive functions in the aging process using the example of rhesus monkeys (Macaca mulatta)
openalex 2019
V. Kh. Khavinson · Clinical Medicine (Russian Journal) · 66 citations
Peptide medicines: past, present, future
openalex 2020
Rahman OF, Lee SJ, Seeds WA
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pubmed
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pmc
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Open Access Article
2 recordspmcAutomated import
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.
Arutjunyan A, Kozina L, Stvolinskiy S, Bulygina Y, Mashkina A, Khavinson V · International journal of clinical and experimental medicine
pmcAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Publication
8 recordspubmedAutomated import
[Comparative analysis of different methods of geroprotective].
Myakotnykh VS, Torgashov MN, Egorin KV, Meshchaninov VN, Gavrilov VI, Borovkova TA, Zvezdina EM, Verzhbitskaya TY, Tkachenko EL
pubmedAutomated import
[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].
Meshchaninov VN, Tkachenko EL, Zharkov SV, Gavrilov IV, Katyreva IuE
pubmedAutomated import
[Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia].
Mendzheritsky AM, Karantysh GV, Ryzhak GA, Prokofiev VN
pubmedAutomated import
[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
Mendzheritskiĭ AM, Karantysh GV, Ryzhak GA, Dem'ianenko SV
pubmedAutomated import
[Effect of peptide geroprotectors on the navigation system learning and caspase-3 in brain structures in rats of different age].
Mendzheritski AM, Karantysh GV, Abramchuk VA, Ryzhak GA
pubmedAutomated import
[Neuroprotective effects of peptides bioregulators in people of various age].
Umnov RS, Lin'kova NS, Khavinson VKh
pubmedAutomated import
[Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades].
Nazimko VA, Morgul' EV, Petrova OA, Sheĭkhova RG, Kozina LS, Savenko MA, Lysenko DS
pubmedAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA
Scholarly Work
6 recordscrossrefAutomated import
PINEALON - PEPTIDE REGULATION OF COGNITIVE ABILITIES OF MACAQUES
Tamara Kuznetsova, Inna Golubeva, Vladimir Khavinson · LCC MAKS Press
crossrefAutomated import
Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes
G. V. Karantysh, M. P. Fomenko, A. M. Menzheritskii, V. N. Prokof’ev, G. A. Ryzhak, E. V. Butenko · Pleiades Publishing Ltd
crossrefAutomated import
INFLUENCE OF PINEALON ON EXPRESSION OF GENES OF PRO- AND ANTIOXIDANT ENZYMES AND FREE RADICAL PROCESSES IN RATS IN THE MODEL OF SUGAR DIABETES
The article presents an analysis of the effect of pinealon on free radical processes and the level of expression of the SOD1, GPX4 and GSR genes in the rat hippocampus in a model of streptozotocininduced diabetes (type I...
crossrefAutomated import
The influence of the Pinealon tripeptide on the rehabilitation of cognitive functions in the aging process using the example of rhesus monkeys (Macaca mulatta)
Tamara G. Kuznetsova, Inna Y. Golubeva, Svetlana V. Trofimova, V. Khavinson, Vyacheslav T. Shuvaev · Moscow University Press
crossrefAutomated import
Pinealon corrects hyperhomocysteinemia-induced disturbances of the diurnal dynamics of hypothalamic norepinephrine content in female rats
A. V. Korenevskii, A. V. Arutyunyan, Yu. P. Milyutina, I. V. Zaloznyaya, L. S. Kozina · Pleiades Publishing Ltd
crossrefAutomated import
Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes
The synthetic tripeptide pinealon (Glu-Asp-Arg) demonstrates dose-dependent restriction of reactive oxygen species (ROS) accumulation in cerebellar granule cells, neutrophils, and pheochromocytoma (PC12) cells, induced by oxidative stress stimulated by receptor-dependent or -independent processes. At the same time, pinealon...
Article
8 recordsopenalexAutomated import
Peptide medicines: past, present, future
V. Kh. Khavinson · Clinical Medicine (Russian Journal) · 66 citations
openalexAutomated import
Effect of Pinealon on Learning and Expression of NMDA Receptor Subunit Genes in the Hippocampus of Rats with Experimental Diabetes
G. V. Karantysh, М. П. Фоменко, A. M. Menzheritskii, В. Н. Прокофьев, Galina Anatol’evna Ryzhak, Elena Viktorovna Butenko · Neurochemical Journal · 1 citations
openalexAutomated import
The influence of the Pinealon tripeptide on the rehabilitation of cognitive functions in the aging process using the example of rhesus monkeys (Macaca mulatta)
Tamara G. Kuznetsova, Inna Yu. Golubeva, Svetlana Trofimova, V. Khavinson, Шуваев Вячеслав Тимофеевич · Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta Seria XXIII Antropologia) · 3 citations
openalexAutomated import
Pinealon corrects hyperhomocysteinemia-induced disturbances of the diurnal dynamics of hypothalamic norepinephrine content in female rats
А. В. Кореневский, Aleksandr Vartanovich Arutyunyan, Yu. P. Milyutina, I. V. Zaloznyaya, Lyudmila S. Kozina · Neurochemical Journal · 3 citations
openalexAutomated import
[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].
А. М. Менджерицкий, G. V. Karantysh, Galina Anatol’evna Ryzhak, S V Dem'ianenko · PubMed · 3 citations
openalexAutomated import
Pinealon protects the rat offspring from prenatal hyperhomocysteinemia.
Alexander V. Arutjunyan, Lyudmila S. Kozina, Sergey Stvolinskiy, Yelena Bulygina, Anna P. Mashkina, Vladimir Khavinson · PubMed · 27 citations
openalexAutomated import
Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA
Larisa Ivanovna Fedoreyeva, Igor I. Kireev, V. Kh. Khavinson, B. F. Vanyushin · Biochemistry (Moscow) · 65 citations
openalexAutomated import
Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes
V. Khavinson, Y. Ribakova, К.Ю. Кулебякин, Elizaveta A. Vladychenskaya, Lyudmila S. Kozina, Alexander V. Arutjunyan et al. · Rejuvenation Research · 17 citations
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Recent PubMed records
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.PMID 41490200 · 2026 Jan 1[Comparative analysis of different methods of geroprotective].PMID 28539017 · 2016[EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION].PMID 26390612 · 2015[Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia].PMID 28509493 · 2015[Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon].PMID 25051764 · 2014Registered clinical studies
Reviewed UniProt records
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