Research context
A synthetic peptide studied in preclinical neurobiology and stress-response research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Neuroscience
Selank
A synthetic peptide studied in preclinical neurobiology and stress-response research.
38 connected records38 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Konstantinopolsky MA, Chernyakova IV, Kolik LG
Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.
pubmed 2022
Doyno CR, White CM
Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.
pubmed 2021
Mukhina AY, Mishina ES, Bobyntsev II, Medvedeva OA, Svishcheva MV, Kalutskii PV, Andreeva LA, Myasoedov NF
Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.
pubmed 2020
Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA, Aleksandrovna BO, Fedorovich MN, Aleksandrovna AL
The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.
pubmed 2026
Panikratova YR, Lebedeva IS, Sokolov OY, Rumshiskaya AD, Kupriyanov DA, Kost NV, Myasoedov NF
Functional Connectomic Approach to Studying Selank and Semax Effects.
pubmed 2020
Vanhee C, Francotte A, Janvier S, Deconinck E
The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.
pubmed 2020
Kolik LG, Nadorova AV, Antipova TA, Kruglov SV, Kudrin VS, Durnev AD
Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.
pubmed 2019
This study will compare the safety and efficacy of Brivaracetam at flexible dose with Placebo in subjects suffering from Epilepsy.
Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From Epilepsy
clinicaltrials 2007
This randomized controlled trial investigates the neural and psychophysiological mechanisms of Imagery Rescripting (ImRs) in individuals with high fear of failure. Participants (N=81, aged 21-34) were randomized to ImRs or an active control condition. The intervention targeted autobiographical memories of parental criticism across four sessions...
Neural Mechanisms and Efficacy of Imagery Rescripting for Fear of Failure
clinicaltrials 2025
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation (tRNS) and transcranial direct current stimulation (tDCS) over bilateral temporo-parietal cortex (TPC), cerebral...
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
clinicaltrials 2023
Mild to moderate hearing loss remains undertreated, largely because of the high cost of hearing aids. A promising and much less expensive alternative is the use of personal sound amplification products (PSAPs), which are electronic, portable, over-the-counter devices that amplify sound. Studies have shown that...
Effects of PSAPs on Speech Processing
clinicaltrials 2021
The purpose of this study is to investigate the impact of rapid elevation to 3,800 meters on the cognitive function of low-altitude residents through a plateau field and plain control study, and explore the objective indicators related to the impaired cognitive function.
The Study on Effects of Acute Exposure to High Altitude Hypoxia on Cognitive Function in Lowlanders
clinicaltrials 2022
The aim of our study is to examine the effects of balance exercises performed in virtual and real environments on visual-spatial attention and mental rotation in healthy young adult individuals using EEG brain oscillations.
The Effect of Balance Exercises on Cognitive Function
clinicaltrials 2023
The study aims at testing a Neurofeedback (NF) training specifically designed for inducing a functional hemispheric imbalance of the tempo-parietal regions in individuals with dyslexia. A randomized clinical trial aimed at comparing two experimental conditions is described: a) Left theta/beta NF training in combination with...
Neurofeedback Training for Dyslexia
clinicaltrials 2021
This study will evaluate the efficacy and safety of Brivaracetam to support the submission file in the indication of adjunctive treatment in adolescents and adults with partial onset seizures.
Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures
clinicaltrials 2007
Background: \- The brain has natural rhythms called brain waves. An electroencephalogram (EEG) can record these rhythms. When people identify the picture of a familiar object shown on a computer screen, the communication between certain regions of the brain increases. An EEG can detect these...
Effects of Transcranial Magnetic Stimulation on Object Recognition
clinicaltrials 2012
This study aims to compare the effectiveness of two telephone-based psychotherapy (Tel-PT) interventions for patients with mild to moderate depression. Both interventions consist of one personal session and weekly to bi-weekly 8-10 telephone sessions with a licensed cognitive-behavioral psychotherapist accompanied by the study of educational...
Trial of Telephone-based Psychotherapy for Depression With and Without Adjunctive Supportive Mail
clinicaltrials 2013
Filatova E, Kasian A, Kolomin T, Rybalkina E, Alieva A, Andreeva L, Limborska S, Myasoedov N, Pavlova G, Slominsky P, Shadrina M · Frontiers in pharmacology
GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.
pmc 2026
Kasian A, Kolomin T, Andreeva L, Bondarenko E, Myasoedov N, Slominsky P, Shadrina M · Behavioural neurology
Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats.
pmc 2026
Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P · Frontiers in pharmacology
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.
pmc 2026
P.M. Klodt · Elsevier BV
P.3.018 Neuropharmacological effects of heptapeptide Selank on the neurotransmitter content in brain structures of Wistar rats
crossref 2005
Post-COVID syndrome develops after a COVID-19 infection, and is also observed in cases of mild or asymptomatic course of the disease. The most common symptoms of bridge syndrome are asthenia and decreased performance, with further development of cognitive deficit. Taking into account the leading role...
POST-COVID SYNDROME, POSSIBILITIES FOR THERAPY OF ASTHENIC DISORDERS WITH SELANK
crossref 2024
Background Adjustment disorder (AD) is one of the most common mental disorders. Considering the social and economic situation in Ukraine at present, in almost 50% of the population, there are non-psychotic mental health disorders, and this number tends to increase. Individual risk factors that are...
The effectiveness of selank in the treatment of adjustment disorder
crossref 2018
S. V. Koroleva, N. F. Mjasoedov · Pleiades Publishing Ltd
Physiological Effects of Selank and Its Fragments
crossref 2019
T. Kolomin, M. Shadrina, D. Grosu · International Society for Clinical Physiology and Pathology
Transcriptomic reaction of the rat hippocampus and spleen to singular and course injection of selank peptide
crossref 2023
T.P. Semenova, I.I. Kozlovsky, A.V. Zuikov, E.N. Karavaev · Elsevier BV
P.3.003 The effect of Selank on the seasonal depressed animal behaviour
crossref 2005
T. N. Sollertinskaja, M. V. Shorochov, N. F. Miasoedov · American Psychological Association (APA)
Stress and the cerebroprotective effects of cortexin and selank brain function disturbances in the ascending row of mammals
crossref 2007
G.G. Neznamov, E.S. Teleshova, V.K. Bochkarev, V.V. Koschelev, T.S. Syunyakov · Elsevier BV
P.3.036 Novel anxiolytic Selank: Results of thePhase II clinical trials
crossref 2005
Anastasiya Volkova, Maria I. Shadrina, Timur A. Kolomin, Lyudmila A. Andreeva, Svetlana Limborska, Nikolai F. Myasoedov et al. · Frontiers in Pharmacology · 19 citations
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
openalex 2016
Marina M. Kozlovskaya, И. И. Козловский, Елена Артуровна Вальдман, С. Б. Середенин · Neuroscience and Behavioral Physiology · 19 citations
Selank and Short Peptides of the Tuftsin Family in the Regulation of Adaptive Behavior in Stress
openalex 2003
T. V. V’yunova, Л. А. Андреева, Konstantin V. Shevchenko, Nikolai F. Myasoedov · Protein and Peptide Letters · 13 citations
Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity
openalex 2018
Rahman OF, Lee SJ, Seeds WA
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pubmed
Uchakina On, Uchakin Pn, Miasoedov Nf, L A Andreeva, V E Shcherbenko, Marina V. Mezentseva et al. · PubMed · 10 citations
[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders].
openalex 2008
V. E. Medvedev, Olessya N. Tereshchenko, Н. В. Кост, A Yu Ter-Israelyan, E V Gushanskaya, I K Chobanu et al. · S S Korsakov Journal of Neurology and Psychiatry · 9 citations
Optimization of the treatment of anxiety disorders with selank
openalex 2015
A. A. Zozulya, Н. В. Кост, Oleg Yu. Sokolov, Marina V. Gabaeva, Igor A. Grivennikov, L. N. Andreeva et al. · Bulletin of Experimental Biology and Medicine · 15 citations
The Inhibitory Effect of Selank on Enkephalin-Degrading Enzymes as a Possible Mechanism of Its Anxiolytic Activity
openalex 2001
Cassandra R. Doyno, Charles Michael White · The Journal of Clinical Pharmacology · 25 citations
Sedative‐Hypnotic Agents That Impact Gamma‐Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma‐Hydroxybutyric Acid, Phenibut, and Selank
openalex 2021
Ershov Fi, Peter Uchakin, Olga N. Uchakina, Marina V. Mezentseva, Ludmila A. Alekseeva, Николай Федорович Мясоедов · PubMed · 9 citations
[Antiviral activity of immunomodulator Selank in experimental influenza infection].
openalex 2009
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pmc
Connected data hub
Records with source provenance.
Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.
Open Access Article
4 recordspmcAutomated import
GABA, Selank, and Olanzapine Affect the Expression of Genes Involved in GABAergic Neurotransmission in IMR-32 Cells.
Filatova E, Kasian A, Kolomin T, Rybalkina E, Alieva A, Andreeva L, Limborska S, Myasoedov N, Pavlova G, Slominsky P, Shadrina M · Frontiers in pharmacology
pmcAutomated import
Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats.
Kasian A, Kolomin T, Andreeva L, Bondarenko E, Myasoedov N, Slominsky P, Shadrina M · Behavioural neurology
pmcAutomated import
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission.
Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P · Frontiers in pharmacology
pmcAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Publication
8 recordspubmedAutomated import
The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.
Leonidovna YA, Aleksandrovna SM, Aleksandrovna TA, Aleksandrovna BO, Fedorovich MN, Aleksandrovna AL
pubmedAutomated import
Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.
Konstantinopolsky MA, Chernyakova IV, Kolik LG
pubmedAutomated import
Sedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.
Doyno CR, White CM
pubmedAutomated import
Morphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.
Mukhina AY, Mishina ES, Bobyntsev II, Medvedeva OA, Svishcheva MV, Kalutskii PV, Andreeva LA, Myasoedov NF
pubmedAutomated import
The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind.
Vanhee C, Francotte A, Janvier S, Deconinck E
pubmedAutomated import
Functional Connectomic Approach to Studying Selank and Semax Effects.
Panikratova YR, Lebedeva IS, Sokolov OY, Rumshiskaya AD, Kupriyanov DA, Kost NV, Myasoedov NF
pubmedAutomated import
Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats.
Kolik LG, Nadorova AV, Antipova TA, Kruglov SV, Kudrin VS, Durnev AD
pubmedAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA
Clinical Trial
10 recordsclinicaltrialsAutomated import
Neural Mechanisms and Efficacy of Imagery Rescripting for Fear of Failure
This randomized controlled trial investigates the neural and psychophysiological mechanisms of Imagery Rescripting (ImRs) in individuals with high fear of failure. Participants (N=81, aged 21-34) were randomized to ImRs or an active control condition. The intervention targeted autobiographical...
clinicaltrialsAutomated import
The Effect of Balance Exercises on Cognitive Function
The aim of our study is to examine the effects of balance exercises performed in virtual and real environments on visual-spatial attention and mental rotation in healthy young adult individuals using EEG brain oscillations.
clinicaltrialsAutomated import
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation (tRNS) and transcranial direct current stimulation...
clinicaltrialsAutomated import
The Study on Effects of Acute Exposure to High Altitude Hypoxia on Cognitive Function in Lowlanders
The purpose of this study is to investigate the impact of rapid elevation to 3,800 meters on the cognitive function of low-altitude residents through a plateau field and plain control study, and explore the objective indicators related to...
clinicaltrialsAutomated import
Effects of PSAPs on Speech Processing
Mild to moderate hearing loss remains undertreated, largely because of the high cost of hearing aids. A promising and much less expensive alternative is the use of personal sound amplification products (PSAPs), which are electronic, portable, over-the-counter devices...
clinicaltrialsAutomated import
Neurofeedback Training for Dyslexia
The study aims at testing a Neurofeedback (NF) training specifically designed for inducing a functional hemispheric imbalance of the tempo-parietal regions in individuals with dyslexia. A randomized clinical trial aimed at comparing two experimental conditions is described: a)...
clinicaltrialsAutomated import
Trial of Telephone-based Psychotherapy for Depression With and Without Adjunctive Supportive Mail
This study aims to compare the effectiveness of two telephone-based psychotherapy (Tel-PT) interventions for patients with mild to moderate depression. Both interventions consist of one personal session and weekly to bi-weekly 8-10 telephone sessions with a licensed cognitive-behavioral...
clinicaltrialsAutomated import
Effects of Transcranial Magnetic Stimulation on Object Recognition
Background: \- The brain has natural rhythms called brain waves. An electroencephalogram (EEG) can record these rhythms. When people identify the picture of a familiar object shown on a computer screen, the communication between certain regions of the...
clinicaltrialsAutomated import
Brivaracetam as add-on Treatment in Adolescents and Adults Suffering From Epilepsy
This study will compare the safety and efficacy of Brivaracetam at flexible dose with Placebo in subjects suffering from Epilepsy.
clinicaltrialsAutomated import
Double-blind, Randomized Study Evaluating the Efficacy and Safety of Brivaracetam in Adults With Partial Onset Seizures
This study will evaluate the efficacy and safety of Brivaracetam to support the submission file in the indication of adjunctive treatment in adolescents and adults with partial onset seizures.
Scholarly Work
8 recordscrossrefAutomated import
POST-COVID SYNDROME, POSSIBILITIES FOR THERAPY OF ASTHENIC DISORDERS WITH SELANK
Post-COVID syndrome develops after a COVID-19 infection, and is also observed in cases of mild or asymptomatic course of the disease. The most common symptoms of bridge syndrome are asthenia and decreased performance, with further development of cognitive...
crossrefAutomated import
Transcriptomic reaction of the rat hippocampus and spleen to singular and course injection of selank peptide
T. Kolomin, M. Shadrina, D. Grosu · International Society for Clinical Physiology and Pathology
crossrefAutomated import
Physiological Effects of Selank and Its Fragments
S. V. Koroleva, N. F. Mjasoedov · Pleiades Publishing Ltd
crossrefAutomated import
The effectiveness of selank in the treatment of adjustment disorder
Background Adjustment disorder (AD) is one of the most common mental disorders. Considering the social and economic situation in Ukraine at present, in almost 50% of the population, there are non-psychotic mental health disorders, and this number tends...
crossrefAutomated import
Stress and the cerebroprotective effects of cortexin and selank brain function disturbances in the ascending row of mammals
T. N. Sollertinskaja, M. V. Shorochov, N. F. Miasoedov · American Psychological Association (APA)
crossrefAutomated import
P.3.018 Neuropharmacological effects of heptapeptide Selank on the neurotransmitter content in brain structures of Wistar rats
P.M. Klodt · Elsevier BV
crossrefAutomated import
P.3.003 The effect of Selank on the seasonal depressed animal behaviour
T.P. Semenova, I.I. Kozlovsky, A.V. Zuikov, E.N. Karavaev · Elsevier BV
crossrefAutomated import
P.3.036 Novel anxiolytic Selank: Results of thePhase II clinical trials
G.G. Neznamov, E.S. Teleshova, V.K. Bochkarev, V.V. Koschelev, T.S. Syunyakov · Elsevier BV
Article
8 recordsopenalexAutomated import
Sedative‐Hypnotic Agents That Impact Gamma‐Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma‐Hydroxybutyric Acid, Phenibut, and Selank
Cassandra R. Doyno, Charles Michael White · The Journal of Clinical Pharmacology · 25 citations
openalexAutomated import
Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity
T. V. V’yunova, Л. А. Андреева, Konstantin V. Shevchenko, Nikolai F. Myasoedov · Protein and Peptide Letters · 13 citations
openalexAutomated import
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
Anastasiya Volkova, Maria I. Shadrina, Timur A. Kolomin, Lyudmila A. Andreeva, Svetlana Limborska, Nikolai F. Myasoedov et al. · Frontiers in Pharmacology · 19 citations
openalexAutomated import
Optimization of the treatment of anxiety disorders with selank
V. E. Medvedev, Olessya N. Tereshchenko, Н. В. Кост, A Yu Ter-Israelyan, E V Gushanskaya, I K Chobanu et al. · S S Korsakov Journal of Neurology and Psychiatry · 9 citations
openalexAutomated import
[Antiviral activity of immunomodulator Selank in experimental influenza infection].
Ershov Fi, Peter Uchakin, Olga N. Uchakina, Marina V. Mezentseva, Ludmila A. Alekseeva, Николай Федорович Мясоедов · PubMed · 9 citations
openalexAutomated import
[Immunomodulatory effects of selank in patients with anxiety-asthenic disorders].
Uchakina On, Uchakin Pn, Miasoedov Nf, L A Andreeva, V E Shcherbenko, Marina V. Mezentseva et al. · PubMed · 10 citations
openalexAutomated import
Selank and Short Peptides of the Tuftsin Family in the Regulation of Adaptive Behavior in Stress
Marina M. Kozlovskaya, И. И. Козловский, Елена Артуровна Вальдман, С. Б. Середенин · Neuroscience and Behavioral Physiology · 19 citations
openalexAutomated import
The Inhibitory Effect of Selank on Enkephalin-Degrading Enzymes as a Possible Mechanism of Its Anxiolytic Activity
A. A. Zozulya, Н. В. Кост, Oleg Yu. Sokolov, Marina V. Gabaeva, Igor A. Grivennikov, L. N. Andreeva et al. · Bulletin of Experimental Biology and Medicine · 15 citations
Live discovery
Latest research signals
Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
Recent PubMed records
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.PMID 41490200 · 2026 Jan 1Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats.PMID 36322304 · 2022 OctSedative-Hypnotic Agents That Impact Gamma-Aminobutyric Acid Receptors: Focus on Flunitrazepam, Gamma-Hydroxybutyric Acid, Phenibut, and Selank.PMID 34396551 · 2021 AugMorphological Changes in the Large Intestine of Rats Subjected to Chronic Restraint Stress and Treated with Selank.PMID 32651826 · 2020 JunThe Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress.PMID 32621722 · 2021Registered clinical studies
Effects of Transcranial Magnetic Stimulation on Object RecognitionNCT01747200 · COMPLETEDNeural Mechanisms and Efficacy of Imagery Rescripting for Fear of FailureNCT07196085 · COMPLETEDEffects of PSAPs on Speech ProcessingNCT05076045 · COMPLETEDReviewed UniProt records
Responsible use of information
Fitzbio provides educational and research reference material. It does not diagnose, prescribe or replace advice from a qualified healthcare professional.