Research context
A synthetic ACTH fragment studied in neuroscience and cognitive research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Neuroscience
Semax
A synthetic ACTH fragment studied in neuroscience and cognitive research.
25 connected records25 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Epilepsy is a disruption of brain function that is characterized by abnormal depolarization of neurons. One signs of epilepsy is seizures, it is caused by brain injury. Epilepsy can cause morbidity and mortality, so many drugs used to treat epilepsy. But these drugs have negative...
Semax for Epilepsy Treatment
crossref 2020
Mohanta Z, Tressler CM, Gori S, Singh A, Stabinska J, Bo S, Karbalaei S, Sall S, Gilad A, Bertoni HL, Gale E, Glunde K, McMahon MT
Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.
pubmed 2026
Sheludchenko VM, Matyushchenko AG, Alharki L, Baryshev KV, Balkar SS, Makarova MA, Alenov MM, Harki YA
[Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome].
pubmed 2026
Liang Y, Liu B, Ma H, Pan L, He A, Dong Y, Man Q, Li J
Multi-Layer Magnetic Shields Based on Fe-Based Nanocrystalline and Co-Based Amorphous Ribbons.
pubmed
Arcos I, Walter A, Marc T, Clusellas N, Puigdollers A
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.
pubmed
Radchenko AI, Kuzubova EV, Apostol AA, Mitkevich VA, Andreeva LA, Limborska SA, Stepenko YV, Shmigerova VS, Solin AV, Korokin MV, Pokrovskii MV, Myasoedov NF, Makarov AA
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
pubmed
Asadullah A, Bajamal AH, Parenrengi MA, Turchan A, Utomo B, Sudiana IK, Subagio EA
Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats).
pubmed 2026
Arcos I, Walter A, Marc T, Clusellas N, Puigdollers A · Journal of clinical medicine
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.
pmc
Radchenko AI, Kuzubova EV, Apostol AA, Mitkevich VA, Andreeva LA, Limborska SA, Stepenko YV, Shmigerova VS, Solin AV, Korokin MV, Pokrovskii MV, Myasoedov NF, Makarov AA · Acta naturae
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
pmc
Filippenkov IB, Shpetko YY, Ales DA, Stavchansky VV, Denisova AE, Yuzhakov VV, Fomina NK, Gubsky LV, Andreeva LA, Myasoedov NF, Limborska SA, Dergunova LV · International journal of molecular sciences
Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage.
pmc
Tomasello MF, Di Rosa MC, Naletova I, Sciacca MFM, Giuffrida A, Maccarrone G, Attanasio F · Bioinorganic chemistry and applications
Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing.
pmc 2026
Dmitrieva VG, Povarova OV, Skvortsova VI, Limborska SA, Myasoedov NF, Dergunova LV · Cellular and molecular neurobiology
Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia.
pmc 2010
Filippenkov IB, Shpetko YY, Stavchansky VV, Denisova AE, Gubsky LV, Andreeva LA, Myasoedov NF, Limborska SA, Dergunova LV · Biomedicines
ACTH-like Peptides Compensate Rat Brain Gene Expression Profile Disrupted by Ischemia a Day After Experimental Stroke.
pmc
· Siree Journals
Correction of Experimental Hypertensive Neuroretinopathy with Semax
crossref 2022
· American Chemical Society (ACS)
Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models
crossref
A. V. Orlov, A. E. Khomutov, I. V. Mukhina, Yu. B. Zimin, S. B. Parin, D. V. Kozin · Springer Science and Business Media LLC
Effect of semax and semax-heparin mixture on isolated heart activity after total ischemia in rats
crossref 1999
· ECO-Vector LLC (Publications)
Dynamics of somatosensory evoked potentials during treatment with Semax in a patient with left hemispheric ischemic stroke:
crossref
· Acta Naturae Ltd
Fig. 1. The experiment design in the study investigating the effects of Semax and the Heptapeptide on APP/PS1 mice
crossref
Mark Konstantinopolsky · Morressier
ACTH4-10 analogue Semax and adamantane derivative hemantane produce significant reduction of withdrawal signs in morphine-dependent rats
crossref 2017
Jia-Dong Zhang, Chi-Yin Chow · Institute of Electrical and Electronics Engineers (IEEE)
SEMAX: Multi-Task Learning for Improving Recommendations
crossref 2019
Willis J, Vu N
Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.
pubmed
Mavrych V, Shypilova I, Bolgova O
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
pubmed 2026
Rahman OF, Lee SJ, Seeds WA
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pubmed
Mavrych V, Shypilova I, Bolgova O · Frontiers in aging
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
pmc 2026
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
pmc
Connected data hub
Records with source provenance.
Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.
Open Access Article
8 recordspmcAutomated import
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Mavrych V, Shypilova I, Bolgova O · Frontiers in aging
pmcAutomated import
Semax, a Copper Chelator Peptide, Decreases the Cu(II)-Catalyzed ROS Production and Cytotoxicity of aβ by Metal Ion Stripping and Redox Silencing.
Tomasello MF, Di Rosa MC, Naletova I, Sciacca MFM, Giuffrida A, Maccarrone G, Attanasio F · Bioinorganic chemistry and applications
pmcAutomated import
Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia.
Dmitrieva VG, Povarova OV, Skvortsova VI, Limborska SA, Myasoedov NF, Dergunova LV · Cellular and molecular neurobiology
pmcAutomated import
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.
Arcos I, Walter A, Marc T, Clusellas N, Puigdollers A · Journal of clinical medicine
pmcAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
pmcAutomated import
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
Radchenko AI, Kuzubova EV, Apostol AA, Mitkevich VA, Andreeva LA, Limborska SA, Stepenko YV, Shmigerova VS, Solin AV, Korokin MV, Pokrovskii MV, Myasoedov NF, Makarov AA · Acta naturae
pmcAutomated import
Genes That Associated with Action of ACTH-like Peptides with Neuroprotective Potential in Rat Brain Regions with Different Degrees of Ischemic Damage.
Filippenkov IB, Shpetko YY, Ales DA, Stavchansky VV, Denisova AE, Yuzhakov VV, Fomina NK, Gubsky LV, Andreeva LA, Myasoedov NF, Limborska SA, Dergunova LV · International journal of molecular sciences
pmcAutomated import
ACTH-like Peptides Compensate Rat Brain Gene Expression Profile Disrupted by Ischemia a Day After Experimental Stroke.
Filippenkov IB, Shpetko YY, Stavchansky VV, Denisova AE, Gubsky LV, Andreeva LA, Myasoedov NF, Limborska SA, Dergunova LV · Biomedicines
Publication
9 recordspubmedAutomated import
Quantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.
Mohanta Z, Tressler CM, Gori S, Singh A, Stabinska J, Bo S, Karbalaei S, Sall S, Gilad A, Bertoni HL, Gale E, Glunde K, McMahon MT
pubmedAutomated import
[Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome].
Sheludchenko VM, Matyushchenko AG, Alharki L, Baryshev KV, Balkar SS, Makarova MA, Alenov MM, Harki YA
pubmedAutomated import
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Mavrych V, Shypilova I, Bolgova O
pubmedAutomated import
Effect of ACTH4-10Pro8-Gly9-Pro10 on anti-inflammatory cytokine (IL-4, IL-10, IL-13) expression in acute spinal cord injury models (male Sprague Dawley rats).
Asadullah A, Bajamal AH, Parenrengi MA, Turchan A, Utomo B, Sudiana IK, Subagio EA
pubmedAutomated import
Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.
Willis J, Vu N
pubmedAutomated import
Multi-Layer Magnetic Shields Based on Fe-Based Nanocrystalline and Co-Based Amorphous Ribbons.
Liang Y, Liu B, Ma H, Pan L, He A, Dong Y, Man Q, Li J
pubmedAutomated import
Digitally Guided Hybrid Maxillary Expansion with Supragingival Mandibular Miniplates for Class III Correction in Late Adolescents: A Pilot Clinical Study.
Arcos I, Walter A, Marc T, Clusellas N, Puigdollers A
pubmedAutomated import
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA
pubmedAutomated import
The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease.
Radchenko AI, Kuzubova EV, Apostol AA, Mitkevich VA, Andreeva LA, Limborska SA, Stepenko YV, Shmigerova VS, Solin AV, Korokin MV, Pokrovskii MV, Myasoedov NF, Makarov AA
Scholarly Work
8 recordscrossrefAutomated import
Correction of Experimental Hypertensive Neuroretinopathy with Semax
· Siree Journals
crossrefAutomated import
Semax for Epilepsy Treatment
Epilepsy is a disruption of brain function that is characterized by abnormal depolarization of neurons. One signs of epilepsy is seizures, it is caused by brain injury. Epilepsy can cause morbidity and mortality, so many drugs used to...
crossrefAutomated import
SEMAX: Multi-Task Learning for Improving Recommendations
Jia-Dong Zhang, Chi-Yin Chow · Institute of Electrical and Electronics Engineers (IEEE)
crossrefAutomated import
ACTH4-10 analogue Semax and adamantane derivative hemantane produce significant reduction of withdrawal signs in morphine-dependent rats
Mark Konstantinopolsky · Morressier
crossrefAutomated import
Effect of semax and semax-heparin mixture on isolated heart activity after total ischemia in rats
A. V. Orlov, A. E. Khomutov, I. V. Mukhina, Yu. B. Zimin, S. B. Parin, D. V. Kozin · Springer Science and Business Media LLC
crossrefAutomated import
Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models
· American Chemical Society (ACS)
crossrefAutomated import
Dynamics of somatosensory evoked potentials during treatment with Semax in a patient with left hemispheric ischemic stroke:
· ECO-Vector LLC (Publications)
crossrefAutomated import
Fig. 1. The experiment design in the study investigating the effects of Semax and the Heptapeptide on APP/PS1 mice
· Acta Naturae Ltd
Live discovery
Latest research signals
Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
Recent PubMed records
[Expert Council resolution: adjunctive pharmacotherapy for hyperkinetic disorders (attention deficit hyperactivity disorder) in children and adolescents].PMID 42910684 · 2026[Changes in retinal light sensitivity and morphometry during surgical treatment of primary glaucoma with physiotherapeutic stimulation].PMID 42885627 · 2026Synthetic Peptides in Pharmacy Compounding: Analysis of PCAC Recommendations and Industry Safety Standards.PMID 42752426 · 2026 Jul-AugQuantitative MRI Pharmacokinetic Modeling and MALDI Mass Spectrometry Imaging Biodistribution of a pH Mapping MRI Contrast Agent.PMID 42559144 · 2026[Effect of a combined physiotherapeutic approach on changes in functional parameters after endovitreal surgery of rhegmatogenous retinal detachment with a favorable anatomical outcome].PMID 42366656 · 2026Registered clinical studies
Reviewed UniProt records
Responsible use of information
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