Research context
A thymic peptide preparation studied in immunology and bioregulation research.
Regulatory note: Verify local laws, product approval and professional guidance before any human use. This profile is not a recommendation for use.
Immune research
Thymalin
A thymic peptide preparation studied in immunology and bioregulation research.
30 connected records30 graded citations0 external identifiers
Evidence map
Claims linked to original records.
Evidence levels describe study design. They do not by themselves establish safety or effectiveness.
Boiko AA, Malanchuk VA, Myroshnychenko MS, Markovska OV, Shapkin AS, Marakushyn DI
Expression features of T-lymphocytes, B-lymphocytes and macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defect with hydroxyapatite-containing osteotropic material and thymalin injecting the surrounding soft tissues.
pubmed 2026
Boiko AA, Malanchuk VA, Myroshnychenko MS
Reparative osteogenesis in mandible in cases of filling a bone defect with hydroxyapatite-containing osteotropic material and injecting the surrounding soft tissues with thymalin: experimental and morphological study.
pubmed 2026
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A
The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.
pubmed
Kuznik BI, Shapovalov KG, Smolyakov YN, Lukyanov SA, Tereshkov PP, Kazantseva LS, Linkova NS
[Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin.].
pubmed 2026
Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E
Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.
pubmed
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E
Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19.
pubmed 2021
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
pubmed 2020
Pinelis IS, Pinelis YI, Kuznik BI, Iordanishvili AK, Vasiliev MA
[Age features of bioregulatory therapy of dental diseases.].
pubmed 2026
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A · International journal of molecular sciences
The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.
pmc
Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E · International journal of molecular sciences
Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.
pmc
Kuznik B, Khavinson V, Shapovalov K, Linkova N, Lukyanov S, Smolyakov Y, Tereshkov P, Shapovalov Y, Konnov V, Tsybikov N · Advances in Gerontology
Peptide Drug Thymalin Regulates Immune Status in Severe COVID-19 Older Patients.
pmc 2026
Khavinson VK, Linkova NS, Chalisova NI, Ivko OM · Biology Bulletin Reviews
The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity.
pmc 2026
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E · Stem cell reviews and reports
Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19.
pmc 2021
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM · Bulletin of experimental biology and medicine
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
pmc 2020
The situation with the COVID-19 pandemic in the world is still tense. Due to the peculiarities of its pathogens, there is a low efficiency in the use of available specific etiotropic drugs, which leads to the need to search for new active means of combating...
Effectiveness of the immunomodulator thymalin in experimental coronavirus infection
crossref 2022
Sergey Lukyanov, Konstantine Shapovalov, Pavel Tereshkov, Yuri Smolyakov, Ayagma Vanchikova, Boris Kuznik · European Respiratory Society
Thymalin as an immunomodulation option in severe COVID-19
crossref 2021
Magen Eli · BiomedGrid LLC
Immunomodulation with Thymalin in the COVID-19 Re-lated Cytokine Storm: Case Reports
crossref 2020
Modern technologies of industrial animal husbandry imply the most effective use of the reproductive potential of females and obtaining healthy young from them. The limiting factor in achieving this goal are diseases characterized by smoothed symptoms, which complicates their timely diagnosis and therapy, one of...
The effect of the combined use of tulatromycin and thymalin in genital mycoplasmosis in cows on cellular immunity indicators
crossref 2023
Human aging constitutes a multifactorial biological process associated with the progressive interaction among genomic instability, epigenetic alterations, mitochondrial dysfunction, inflammaging, immunosenescence, and neuroendocrine deterioration. Over recent decades, advances in molecular geroscience have increased scientific interest in peptide bioregulators due to their potential effects on cellular...
PEPTIDE BIOREGULATORS, AGING AND HUMAN LONGEVITY: EPITHALON, THYMALIN, THYMOGEN, DSIP, VILON AND VESUGEN IN CIRCADIAN BIOLOGY, TELOMERASE REGULATION AND INFLAMMAGING
crossref 2026
L. I. Anokhova, E. D. Zagorodnaya, A. V. Pateyuk, B. I. Kuznik · SPb RAACI
COMPARATIVE EFFECTS OF THYMOGEN AND THYMALIN UPON IMMUNITY, HAEMOSTASIS AND POSTOPERATIVE ENDOMETRITIS
crossref 2014
Intensive technologies of animal husbandry imply the maximum use of productive qualities of animals, the realization of which is hindered by diseases of various genesis, especially those that are accompanied by a long chronic course. Genital mycoplasmosis of cattle occupies a special place among them....
Changes in the protein spectrum of blood serum of cows with mycoplasmosis when used for the treatment of Tulatromycin and Thymalin
crossref 2024
Z. S. Khlystova, I. I. Kalinina, V. Kh. Khavinson · Springer Science and Business Media LLC
Distribution of the hormonal thymic factor thymalin in human fetal tissues
crossref 1993
Galina V. Zhukova, A. I. Schikhlyarova, Tatiana Albertovna Barteneva, Aleksey N. Shevchenko, Faina M. Zakharyuta · Bulletin of Experimental Biology and Medicine · 10 citations
Effect of Thymalin on the Tumor and Thymus under Conditions of Activation Therapy In Vivo
openalex 2018
V. Kh. Khavinson, Natalia Sergeevna Linkova, Igor Moiseevich Kvetnoy, Victoria Olegovna Polyakova, А. О. Дробинцева, Tatiana V. Kvetnaia et al. · Bulletin of Experimental Biology and Medicine · 7 citations
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells
openalex 2020
Z. S. Khlystova, И. И. Калинина, S. P. Shmeleva · Bulletin of Experimental Biology and Medicine · 6 citations
Thymalin in Developing Respiratory Organs of Human Fetus
openalex 2003
V Kh Khavinson, Vjacheslav G. Morozov · PubMed · 3 citations
[Geroprotective effect of thymalin and epithalamin].
openalex 2002
Mal'khanov Vb, I A Gripas', G Kh Nasibullina, M A Belousova · PubMed · 5 citations
[Use of T-activin and thymalin in the treatment of ophthalmic herpes].
openalex 1992
Khavinson VKh, Kuznik Bi, Volchkov Va, Светлана Александровна Рукавишникова, O. N. Titova, Т. А. Ахмедов et al. · Clinical Medicine (Russian Journal) · 4 citations
Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19
openalex 2021
Tatyana A. Kuznetsova, Natalia N. Besednova, Tatyana S. Zaporozhets, Tatiana P. Smolina, A K Kazha, Л. А. Иванушко · PubMed · 3 citations
[Comparative study of immunomodulatory activity of peptides, tinrostim and thymalin].
openalex 2013
Z. S. Khlystova, И. И. Калинина, S. P. Shmeleva, O. P. Ryabchikov, V. Kh. Khavinson · Bulletin of Experimental Biology and Medicine · 2 citations
Age-Related Changes of Thymalin Content in Human Epidermis
openalex 2002
Connected data hub
Records with source provenance.
Reviewed records carry an admin-reviewed badge. Automated records link back to the provider for independent checking.
Open Access Article
6 recordspmcAutomated import
Peptide Drug Thymalin Regulates Immune Status in Severe COVID-19 Older Patients.
Kuznik B, Khavinson V, Shapovalov K, Linkova N, Lukyanov S, Smolyakov Y, Tereshkov P, Shapovalov Y, Konnov V, Tsybikov N · Advances in Gerontology
pmcAutomated import
The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity.
Khavinson VK, Linkova NS, Chalisova NI, Ivko OM · Biology Bulletin Reviews
pmcAutomated import
Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19.
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E · Stem cell reviews and reports
pmcAutomated import
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM · Bulletin of experimental biology and medicine
pmcAutomated import
The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A · International journal of molecular sciences
pmcAutomated import
Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.
Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E · International journal of molecular sciences
Publication
8 recordspubmedAutomated import
Expression features of T-lymphocytes, B-lymphocytes and macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defect with hydroxyapatite-containing osteotropic material and thymalin injecting the surrounding soft tissues.
Boiko AA, Malanchuk VA, Myroshnychenko MS, Markovska OV, Shapkin AS, Marakushyn DI
pubmedAutomated import
Reparative osteogenesis in mandible in cases of filling a bone defect with hydroxyapatite-containing osteotropic material and injecting the surrounding soft tissues with thymalin: experimental and morphological study.
Boiko AA, Malanchuk VA, Myroshnychenko MS
pubmedAutomated import
[Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin.].
Kuznik BI, Shapovalov KG, Smolyakov YN, Lukyanov SA, Tereshkov PP, Kazantseva LS, Linkova NS
pubmedAutomated import
[Age features of bioregulatory therapy of dental diseases.].
Pinelis IS, Pinelis YI, Kuznik BI, Iordanishvili AK, Vasiliev MA
pubmedAutomated import
Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19.
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E
pubmedAutomated import
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM
pubmedAutomated import
The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A
pubmedAutomated import
Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.
Avolio F, Martinotti S, Khavinson VK, Esposito JE, Giambuzzi G, Marino A, Mironova E, Pulcini R, Robuffo I, Bologna G, Simeone P, Lanuti P, Guarnieri S, Trofimova S, Procopio AD, Toniato E
Scholarly Work
8 recordscrossrefAutomated import
PEPTIDE BIOREGULATORS, AGING AND HUMAN LONGEVITY: EPITHALON, THYMALIN, THYMOGEN, DSIP, VILON AND VESUGEN IN CIRCADIAN BIOLOGY, TELOMERASE REGULATION AND INFLAMMAGING
Human aging constitutes a multifactorial biological process associated with the progressive interaction among genomic instability, epigenetic alterations, mitochondrial dysfunction, inflammaging, immunosenescence, and neuroendocrine deterioration. Over recent decades, advances in molecular geroscience have increased scientific interest in peptide bioregulators...
crossrefAutomated import
Changes in the protein spectrum of blood serum of cows with mycoplasmosis when used for the treatment of Tulatromycin and Thymalin
Intensive technologies of animal husbandry imply the maximum use of productive qualities of animals, the realization of which is hindered by diseases of various genesis, especially those that are accompanied by a long chronic course. Genital mycoplasmosis of...
crossrefAutomated import
The effect of the combined use of tulatromycin and thymalin in genital mycoplasmosis in cows on cellular immunity indicators
Modern technologies of industrial animal husbandry imply the most effective use of the reproductive potential of females and obtaining healthy young from them. The limiting factor in achieving this goal are diseases characterized by smoothed symptoms, which complicates...
crossrefAutomated import
Effectiveness of the immunomodulator thymalin in experimental coronavirus infection
The situation with the COVID-19 pandemic in the world is still tense. Due to the peculiarities of its pathogens, there is a low efficiency in the use of available specific etiotropic drugs, which leads to the need to...
crossrefAutomated import
Thymalin as an immunomodulation option in severe COVID-19
Sergey Lukyanov, Konstantine Shapovalov, Pavel Tereshkov, Yuri Smolyakov, Ayagma Vanchikova, Boris Kuznik · European Respiratory Society
crossrefAutomated import
Immunomodulation with Thymalin in the COVID-19 Re-lated Cytokine Storm: Case Reports
Magen Eli · BiomedGrid LLC
crossrefAutomated import
COMPARATIVE EFFECTS OF THYMOGEN AND THYMALIN UPON IMMUNITY, HAEMOSTASIS AND POSTOPERATIVE ENDOMETRITIS
L. I. Anokhova, E. D. Zagorodnaya, A. V. Pateyuk, B. I. Kuznik · SPb RAACI
crossrefAutomated import
Distribution of the hormonal thymic factor thymalin in human fetal tissues
Z. S. Khlystova, I. I. Kalinina, V. Kh. Khavinson · Springer Science and Business Media LLC
Article
7 recordsopenalexAutomated import
Effect of thymalin on adaptive immunity in complex therapy for patients with COVID-19
Khavinson VKh, Kuznik Bi, Volchkov Va, Светлана Александровна Рукавишникова, O. N. Titova, Т. А. Ахмедов et al. · Clinical Medicine (Russian Journal) · 4 citations
openalexAutomated import
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells
V. Kh. Khavinson, Natalia Sergeevna Linkova, Igor Moiseevich Kvetnoy, Victoria Olegovna Polyakova, А. О. Дробинцева, Tatiana V. Kvetnaia et al. · Bulletin of Experimental Biology and Medicine · 7 citations
openalexAutomated import
Effect of Thymalin on the Tumor and Thymus under Conditions of Activation Therapy In Vivo
Galina V. Zhukova, A. I. Schikhlyarova, Tatiana Albertovna Barteneva, Aleksey N. Shevchenko, Faina M. Zakharyuta · Bulletin of Experimental Biology and Medicine · 10 citations
openalexAutomated import
[Comparative study of immunomodulatory activity of peptides, tinrostim and thymalin].
Tatyana A. Kuznetsova, Natalia N. Besednova, Tatyana S. Zaporozhets, Tatiana P. Smolina, A K Kazha, Л. А. Иванушко · PubMed · 3 citations
openalexAutomated import
Thymalin in Developing Respiratory Organs of Human Fetus
Z. S. Khlystova, И. И. Калинина, S. P. Shmeleva · Bulletin of Experimental Biology and Medicine · 6 citations
openalexAutomated import
Age-Related Changes of Thymalin Content in Human Epidermis
Z. S. Khlystova, И. И. Калинина, S. P. Shmeleva, O. P. Ryabchikov, V. Kh. Khavinson · Bulletin of Experimental Biology and Medicine · 2 citations
openalexAutomated import
[Use of T-activin and thymalin in the treatment of ophthalmic herpes].
Mal'khanov Vb, I A Gripas', G Kh Nasibullina, M A Belousova · PubMed · 5 citations
Other
1 recordsopenalexAutomated import
[Geroprotective effect of thymalin and epithalamin].
V Kh Khavinson, Vjacheslav G. Morozov · PubMed · 3 citations
Live discovery
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Live results from PubMed, ClinicalTrials.gov and UniProt. These may not yet have been reviewed or stored in the Data Hub.
Recent PubMed records
Expression features of T-lymphocytes, B-lymphocytes and macrophages in the post-traumatic regenerate of the mandible rats under conditions of filling a bone defect with hydroxyapatite-containing osteotropic material and thymalin injecting the surrounding soft tissues.PMID 38642352 · 2024Reparative osteogenesis in mandible in cases of filling a bone defect with hydroxyapatite-containing osteotropic material and injecting the surrounding soft tissues with thymalin: experimental and morphological study.PMID 38431810 · 2024The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19.PMID 37686182 · 2023 Aug 29[Morphological compound and indicators of the blood clotting system in severe COVID-19 patients of middle aged and elderly during treatment of Tocilizumab and Thymalin.].PMID 36169363 · 2022Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line.PMID 35408963 · 2022 Mar 25Registered clinical studies
Reviewed UniProt records
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